In silico genome-wide analysis of homeodomain-leucine zipper transcription factors in Cannabis sativa L
Abstract HD-Zip (Homeodomain-Leucine Zipper) is a family of transcription factors unique to higher plants and plays a vital role in…
bioinformatics
In silico analyses of the involvement of GPR55, CB1R and TRPV1: response to THC, contribution to temporal lobe epilepsy, structural modeling and updated evolution
Abstract Introduction: The endocannabinoid (eCB) system is named after the discovery that endogenous cannabinoids bind to the same receptors as…
Challenges to Cannabis sativa Production from Pathogens and Microbes—The Role of Molecular Diagnostics and Bioinformatics
Abstract The increased cultivation of Cannabis sativa L. in North America, represented by high Δ9-tetrahydrocannabinol-containing (high-THC) cannabis genotypes and low-THC-containing…
An approach for collaborative development of a federated biomedical knowledge graph-based question-answering system: Question-of-the-Month challenges
Abstract Knowledge graphs have become a common approach for knowledge representation. Yet, the application of graph methodology is elusive due…
Genome-Wide Identification and Expression Analysis of Homeodomain Leucine Zipper Subfamily IV (HD-ZIP IV) Gene Family in Cannabis sativa L.
Abstract The plant-specific homeodomain zipper family (HD-ZIP) of transcription factors plays central roles in regulating plant development and environmental resistance.…
Comprehensive analysis of the expression and prognosis for APOE in malignancies: A pan-cancer analysis
Abstract Apolipoprotein E (APOE), a gene identified as one of the strongest genetic factors contributing to the risk determinant of…
Identification of the Histone Deacetylases Gene Family in Hemp Reveals Genes Regulating Cannabinoids Synthesis
Abstract Histone deacetylases (HDACs) play crucial roles nearly in all aspects of plant biology, including stress responses, development and growth,…
Identification of prostate cancer specific methylation biomarkers from a multi-cancer analysis
Abstract Background: Detecting prostate cancer at a non-aggressive stage is the main goal of prostate cancer screening. DNA methylation has…
Comparative Investigation of Composition, Antifungal, and Anti-Inflammatory Effects of the Essential Oil from Three Industrial Hemp Varieties from Italian Cultivation
Abstract Industrial hemp is characterized by a huge amount of by-products, such as inflorescences, that may represent high-quality sources of…
Chemical and Bioinformatics Analyses of the Anti-Leishmanial and Anti-Oxidant Activities of Hemp Essential Oil
Abstract Industrial hemp is a multiuse crop that has been widely cultivated to produce fibers and nutrients. The capability of…