Immunotyping of thyroid cancer for clinical outcomes and implications
Abstract Background: Tumor immune microenvironment (TIME) plays a crucial role in cancer development. However, the prognostic significance of immune-related genes…
bioinformatics
LMO2 confers value as a potential immunotherapy marker in pan-cancer analysis and inhibits progression of Clear Cell Renal Cell Carcinoma
Abstract Full pan-cancer analysis of LMO2 with immunotherapeutic target assessment. ZC3h13 mediated m6A modification controls LMO2 expression in ccRCC. LMO2…
In Silico Prioritization of STAT1 3′ UTR SNPs Identifies rs190542524 as a miRNA-Linked Variant with Potential Oncogenic Impact
Abstract Background: Single-nucleotide polymorphisms (SNPs) are associated with multiple disorders and various cancer types. In the context of cancer, alterations…
A pan-cancer analysis targeting the oncogenic role of ATP-binding cassette transporter A1 in human tumors
Abstract Objectives: ABCA1 is involved in the development and progression of a wide range of malignant tumors, so to further…
Pan-cancer analysis of the prognosis and immune infiltration of NSUN7 and its potential function in renal clear cell carcinoma
Abstract Background: NSUN7, an enzyme responsible for the RNA m5c modification, has been recognized as a valuable indicator for predicting…
The Multifaceted Role of lncRNA GAS5: A Pan-Cancer Analysis of Its Diagnostic, Prognostic, and Therapeutic Potential
Abstract Introduction: Cancer is a significant global health problem characterized by increased incidence and large disparities in outcomes. There is…
NFKB1 as a key player in Tumor biology: from mechanisms to therapeutic implications
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s10565-024-09974-2. Article type: Review Article Keywords: NFKB1, Tumor, Literature…
Pan-Cancer Analysis of KANK2: Clinical and Molecular Insights into Tumor Progression and Therapeutic Implications
Abstract Background: KANK2, a gene crucial for cell migration and movement, is implicated in neoplastic and non-neoplastic diseases. This study…
Integrative pan-cancer analysis and experiment validation identified GLS as a biomarker in tumor progression, prognosis, immune microenvironment, and immunotherapy
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-84916-w. Article type: Research Article Keywords: GLS, Pan-cancer analysis,…
Chromosome-level Haploid Assembly of Cannabis sativa L. cv. Pink Pepper
Abstract As molecular research on hemp (Cannabis sativa L.) continues to advance, there is a growing need for the accumulation…