biochemistry

July 20, 2026

Preliminary pharmacokinetic investigations of hydroxylated metabolites after controlled inhalative and oral consumption of hexahydrocannabinol (HHC)

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-026-62767-x. Article type: Research Article Keywords: Hexahydrocannabinol, Cannabinoids, Pharmacokinetics,…

April 2, 2026

Enhancement of fiber content and cannabinoids of hemp using arbuscular mycorrhizal fungi and endophytic fungi

Abstract This study aimed to investigate the efficiency of arbuscular mycorrhizal fungi (AMF) and endophytic fungi to promote growth and…

March 26, 2026

Temperature-dependent gating pathways in TRPV3

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-026-44194-0. Article type: Research Article Keywords: Biochemistry, Biological techniques,…

March 6, 2026

Cannabidiolic acid as a modulator of lipid metabolism in the liver of rats with metabolic-associated steatotic liver disease

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-026-41130-0. Article type: Research Article Keywords: Cannabidiolic acid (CBDA),…

February 13, 2026

Investigating the psychedelic hypothesis of kykeon, the sacred elixir of the Eleusinian Mysteries

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-026-39568-3. Article type: Research Article Keywords: Psychedelic, Eleusinian Mysteries,…

February 9, 2026

Exploring the chemical space around Cannabis sativa L. leaves as a source of bioactive compounds of pharmaceutical interest

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-026-39088-0. Article type: Research Article Keywords: Leaves, Polyphenols, Cannabinoids,…

January 31, 2026

Hemp seed extract exerts cytostatic effects through metabolic stress and autophagy modulation in malignant cells

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-026-37119-4. Article type: Research Article Keywords: Biochemistry, Cancer, Cell…

January 22, 2026

Cannabidiol mitigates high-fat-diet-induced early-stage inflammation in two adipose tissue fat depots of Wistar rats

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-026-36666-0. Article type: Research Article Keywords: Adipose tissue, Cannabidiol,…

December 24, 2025

Cannabidiol perturbs macrophage polarization by interfering with the metabolic flux and PI3K/Akt pathway

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-33360-5. Article type: Research Article Keywords: Cannabidiol, Macrophage, Metabolic…

December 18, 2025

Nitrogen source and solution strength modulate cannabinoid and antioxidant profiles in medicinal cannabis grown in a deep-water culture system

Abstract The optimization of nitrogen nutrition is critical for standardizing the production of bioactive compounds in medicinal Cannabis sativa L.…