Production of Biopolymeric Microparticles to Improve Cannabigerol Bioavailability
Abstract Cannabigerol’s (CBG) therapeutic effects are limited by its poor water solubility and low dissolution rate. To improve these properties,…
bioavailability
Enhanced oral bioavailability of cannabidiol by flexible zein nanoparticles: in vitro and pharmacokinetic studies
Abstract Introduction: Cannabidiol (CBD) has a variety of pharmacological effects including antiepileptic, antispasmodic, anxiolytic and anti-inflammatory among other pharmacological effects.…
Potential Anti-Tumorigenic Properties of Diverse Medicinal Plants against the Majority of Common Types of Cancer
Abstract Globally, cancer is one of the primary causes of both morbidity and mortality. To prevent cancer from getting worse,…
Resources for Human Health from the Plant Kingdom: The Potential Role of the Flavonoid Apigenin in Cancer Counteraction
Abstract Apigenin is one of the most widespread flavonoids in the plant kingdom. For centuries, apigenin-containing plant preparations have been…
Absorption and Bioavailability of Novel UltraShear Nanoemulsion of Cannabidiol in Rats
Abstract Introduction: Cannabidiol (CBD) has several potential benefits and therapeutic uses, especially in pain, inflammation, and anxiety. CBD has high…
Lipid-based oral formulation in capsules to improve the delivery of poorly water-soluble drugs
Abstract Poorly water-soluble drugs demonstrate significant challenge in pharmaceutical development, which is linked to their limited oral bioavailability and therapeutic…
THC-Reduced Cannabis sativa L.—How Does the Solvent Determine the Bioavailability of Cannabinoids Given Orally?
Abstract The bioavailability levels of cannabidiol (CBD) and tetrahydrocannabinol (THC) determine their pharmacological effects. Therefore, for medical purposes, it is…
Antioxidant Effect Assessment and Trans Epithelial Analysis of New Hempseed Protein Hydrolysates
Abstract Hempseed (Cannabis sativa) is one of the most promising sources of plant proteins. It contains approximately 24% (w/w) protein,…
Cannabidiol-Loaded Nanocarriers and Their Therapeutic Applications
Abstract Cannabidiol (CBD), one of the most promising constituents isolated from Cannabis sativa, exhibits diverse pharmacological actions. However, the applications…
Pharmacokinetics of Orally Applied Cannabinoids and Medical Marijuana Extracts in Mouse Nervous Tissue and Plasma: Relevance for Pain Treatment
Abstract Cannabis sativa plants contain a multitude of bioactive substances, which show broad variability between different plant strains. Of the…