A systematic review of protein post-translational modifications in sepsis
Abstract Background: Sepsis originates from the host’s dysregulated response to pathogens, and its pathophysiological mechanisms are extremely complex. Recent research…
auto immune diseases
Pan-cancer analyses reveal genomics and clinical outcome association of the fatty acid oxidation regulators in cancer
Abstract Background: Fatty acid oxidation (FAO) is considered to play a vital part in tumor metabolic reprogramming. But the comprehensive…
Screening tumor stage-specific candidate neoantigens in thyroid adenocarcinoma using integrated exome and transcriptome sequencing
Abstract Background: The incidence of thyroid carcinoma (THCA), the most common endocrine tumor, is continuously increasing worldwide. Although the overall…
Beyond Pain Relief: A Review on Cannabidiol Potential in Medical Therapies
Abstract The phytocannabinoid cannabidiol (CBD) is receiving increasing attention due to its pharmacological properties. Although CBD is extracted from Cannabis…
Neuroimmune proteins can differentiate between tauopathies
Abstract Background: Tauopathies are a group of neurodegenerative diseases where there is pathologic accumulation of hyperphosphorylated tau protein (ptau). The…
Endocannabinoid System Unlocks the Puzzle of Autism Treatment via Microglia
Abstract Autism spectrum disorder (ASD) is a serious neurodevelopmental disorder and characterized by early childhood-onset impairments in social interaction and…
Cannabis, the Endocannabinoid System and Immunity—the Journey from the Bedside to the Bench and Back
Abstract The Cannabis plant contains numerous components, including cannabinoids and other active molecules. The phyto-cannabinoid activity is mediated by the…
Cannabinoids Reduce Inflammation but Inhibit Lymphocyte Recovery in Murine Models of Bone Marrow Transplantation
Abstract Cannabinoids, the biologically active constituents of Cannabis, have potent neuronal and immunological effects. However, the basic and medical research…