Cannabidiol corrects sleep deficits and reduces spontaneous seizures in Angelman syndrome model mice
Abstract The off-label use of cannabidiol (CBD) has outpaced investigation. We assessed the effects of CBD in Angelman syndrome model…
autism spectrum disorders
Cannabidiol blood metabolite levels after cannabidiol treatment are associated with broadband EEG changes and improvements in visuomotor and non-verbal cognitive abilities in boys with autism requiring higher levels of support
Abstract Oral cannabidiol (CBD) treatment has been suggested to alleviate severe symptoms of autism spectrum disorder (ASD). While many CBD…
Therapeutic Use of Cannabis Derivatives and Their Analogs for Autism Spectrum Disorder: A Systematic Review
Abstract Autism spectrum disorders are characterized by some difficulties with social interactions and communication, atypical patterns of behavior, and unusual…
DNA Methylation in Autism Spectrum Disorders: Biomarker or Pharmacological Target?
Abstract Autism spectrum disorder (ASD) is a group of heterogeneous neurodevelopmental disabilities with persistent impairments in cognition, communication, and social…
Cannabidiol is a behavioral modulator in BTBR mouse model of idiopathic autism
Abstract Introduction: The prevalence of Autism Spectrum Disorder (ASD) has drastically risen over the last two decades and is currently…
Individually tailored dosage regimen of full-spectrum Cannabis extracts for autistic core and comorbid symptoms: a real-life report of multi-symptomatic benefits
Abstract Autism Spectrum Disorders (ASD) may significantly impact the well-being of patients and their families. The therapeutic use of cannabis…
Children and adolescents with ASD treated with CBD-rich cannabis exhibit significant improvements particularly in social symptoms: an open label study
Abstract In recent years there has been growing interest in the potential benefits of CBD-rich cannabis treatment for children with…
The Endocannabinoids-Microbiota Partnership in Gut-Brain Axis Homeostasis: Implications for Autism Spectrum Disorders
Abstract The latest years have witnessed a growing interest towards the relationship between neuropsychiatric disease in children with autism spectrum…
Behavioral aspects and neurobiological properties underlying medical cannabis treatment in Shank3 mouse model of autism spectrum disorder
Abstract Autism spectrum disorder (ASD) is a neurodevelopmental disease with a wide spectrum of manifestation. The core symptoms of ASD…
Sperm DNA methylation altered by THC and nicotine: Vulnerability of neurodevelopmental genes with bivalent chromatin
Abstract Men consume the most nicotine and cannabis products but impacts on sperm epigenetics are poorly characterized. Evidence suggests that…