The Neuroglial Dialog Between Cannabinoids and Hemichannels
Abstract The formation of gap junctions was initially thought to be the central role of connexins, however, recent evidence had…
Astrocytes
Modulation of Astrocyte Activity by Cannabidiol, a Nonpsychoactive Cannabinoid
Abstract The astrocytes have gained in recent decades an enormous interest as a potential target for neurotherapies, due to their…
YKL-40 (Chitinase 3-like I) is expressed in a subset of astrocytes in Alzheimer’s disease and other tauopathies
Abstract Background: The innate immune system is known to be involved early in the pathogenesis of Alzheimer’s disease (AD) and…
Cannabinoid Receptor 2 Signaling in Neurodegenerative Disorders: From Pathogenesis to a Promising Therapeutic Target
Abstract As a consequence of an increasingly aging population, the number of people affected by neurodegenerative disorders, such as Alzheimer’s…
Excess cerebral TNF causing glutamate excitotoxicity rationalizes treatment of neurodegenerative diseases and neurogenic pain by anti-TNF agents
Abstract The basic mechanism of the major neurodegenerative diseases, including neurogenic pain, needs to be agreed upon before rational treatments…