Oxidative Stress and Autophagy Mediate Anti-Cancer Properties of Cannabis Derivatives in Human Oral Cancer Cells
Abstract Simple Summary: The legalization of cannabis in 2018 in Canada has generated a heated public debate. The subject is…
Apoptosis
Cannabidiol (CBD) Protects Adipose-Derived Mesenchymal Stem Cells (ASCs) against Endoplasmic Reticulum Stress Development and Its Complications
Abstract Background: Recent studies suggested that individuals with metabolic disorders have altered function of adipocytes and adipose stem cell subpopulations,…
Hemp (Cannabis sativa L., Kompolti cv.) and Hop (Humulus lupulus L., Chinook cv.) Essential Oil and Hydrolate: HS-GC-MS Chemical Investigation and Apoptotic Activity Evaluation
Abstract In this study, essential oils (EOs) and hydrolates (Hys) from Italian hemp (Cannabis sativa L. Kompolti cv.) and hop…
An Examination of the Anti-Cancer Properties of Plant Cannabinoids in Preclinical Models of Mesothelioma
Abstract Simple Summary: Mesothelioma is a deadly disease with few treatment options. Phytocannabinoids derived from the cannabis plant are garnering…
Anti-cancer properties of cannflavin A and potential synergistic effects with gemcitabine, cisplatin, and cannabinoids in bladder cancer
Abstract Introduction: Several studies have shown anti-tumor effects of components present in cannabis in different models. Unfortunately, little is known…
Influence of Inhibition of COX-2-Dependent Lipid Metabolism on Regulation of UVB-Induced Keratinocytes Apoptosis by Cannabinoids
Abstract Inflammation and apoptosis are regulated by similar factors, including ultraviolet B (UVB) radiation and cannabinoids, which are metabolized by…
Mechanisms of Cannabidiol (CBD) in Cancer Treatment: A Review
Abstract Simple Summary: Emerging evidence suggests positive outcomes from the use of CBD as a cancer treatment. CBD can relieve…
Effect of cannabidiol on apoptosis and cellular interferon and interferon-stimulated gene responses to the SARS-CoV-2 genes ORF8, ORF10 and M protein
Abstract Aims: To study effects on cellular innate immune responses to ORF8, ORF10, and Membrane protein (M protein) from the…
Comprehensive Analysis of the Potential Immune-Related Biomarker ATG101 that Regulates Apoptosis of Cholangiocarcinoma Cells After Photodynamic Therapy
Abstract Autophagy related gene 101 (ATG101) plays a significant role in the occurrence and development of tumours by responding to…
Endocannabinoid signaling in glioma
Abstract High‐grade gliomas constitute the most frequent and aggressive form of primary brain cancer in adults. These tumors express cannabinoid…