Cannabidiol Inhibits Tumorigenesis in Cisplatin-Resistant Non-Small Cell Lung Cancer via TRPV2
Abstract Simple Summary: Drug resistance is the key factor contributing to the therapeutic failure of lung cancer and the deaths…
Apoptosis
BRAF-activated WT1 contributes to cancer growth and regulates autophagy and apoptosis in papillary thyroid carcinoma
Abstract Background: Papillary thyroid carcinoma (PTC) is one of most prevalent malignant endocrine neoplasms, and it is associated with a…
15-Lipoxygenase and its metabolites in the pathogenesis of breast cancer: A double-edged sword
Abstract 15-lipoxygenase is one of the key enzymes for the metabolism of unsaturated fatty acids that its manipulation has been…
Cannabidiol Induces Cell Death in Human Lung Cancer Cells and Cancer Stem Cells
Abstract Currently, there is no effective therapy against lung cancer due to the development of resistance. Resistance contributes to disease…
The Endocannabinoid System as a Pharmacological Target for New Cancer Therapies
Abstract Simple Summary: Cannabinoids have been shown to suppress tumour cell proliferation, tumour invasion, metastasis, angiogenesis, chemoresistance and epithelial-mesenchymal transition…
N-Acyl Dopamines Induce Apoptosis in Endometrial Stromal Cells from Patients with Endometriosis
Abstract Endometriosis is characterized by the formation and development of endometrial tissues outside the uterus, based on an imbalance between…
Synergistic Interactions of Cannabidiol with Chemotherapeutic Drugs in MCF7 Cells: Mode of Interaction and Proteomics Analysis of Mechanisms
Abstract Cannabidiol (CBD), a nonpsychoactive phytocannabinoid, has recently emerged as a potential cytotoxic agent in addition to its ameliorative activity…
Disease-Dependent Antiapoptotic Effects of Cannabidiol for Keratinocytes Observed upon UV Irradiation
Abstract Although apoptosis of keratinocytes has been relatively well studied, there is a lack of information comparing potentially proapoptotic treatments…
Cerebroprotein Hydrolysate-I Inhibits Hippocampal Neuronal Apoptosis by Activating PI3K/Akt Signaling Pathway in Vascular Dementia Mice
Abstract Introduction: Vascular dementia (VaD), one of the brain injuries, is difficult to be cured, so it is important to…
A novel mitochondrial Kv1.3–caveolin axis controls cell survival and apoptosis
Abstract The voltage-gated potassium channel Kv1.3 plays an apparent dual physiological role by participating in activation and proliferation of leukocytes…