Mechanisms of Cannabidiol (CBD) in Cancer Treatment: A Review
Abstract Simple Summary: Emerging evidence suggests positive outcomes from the use of CBD as a cancer treatment. CBD can relieve…
Apoptosis
Effect of cannabidiol on apoptosis and cellular interferon and interferon-stimulated gene responses to the SARS-CoV-2 genes ORF8, ORF10 and M protein
Abstract Aims: To study effects on cellular innate immune responses to ORF8, ORF10, and Membrane protein (M protein) from the…
Endocannabinoid signaling in glioma
Abstract High‐grade gliomas constitute the most frequent and aggressive form of primary brain cancer in adults. These tumors express cannabinoid…
Cannabidiol Inhibits Tumorigenesis in Cisplatin-Resistant Non-Small Cell Lung Cancer via TRPV2
Abstract Simple Summary: Drug resistance is the key factor contributing to the therapeutic failure of lung cancer and the deaths…
15-Lipoxygenase and its metabolites in the pathogenesis of breast cancer: A double-edged sword
Abstract 15-lipoxygenase is one of the key enzymes for the metabolism of unsaturated fatty acids that its manipulation has been…
Cannabidiol Induces Cell Death in Human Lung Cancer Cells and Cancer Stem Cells
Abstract Currently, there is no effective therapy against lung cancer due to the development of resistance. Resistance contributes to disease…
The Endocannabinoid System as a Pharmacological Target for New Cancer Therapies
Abstract Simple Summary: Cannabinoids have been shown to suppress tumour cell proliferation, tumour invasion, metastasis, angiogenesis, chemoresistance and epithelial-mesenchymal transition…
N-Acyl Dopamines Induce Apoptosis in Endometrial Stromal Cells from Patients with Endometriosis
Abstract Endometriosis is characterized by the formation and development of endometrial tissues outside the uterus, based on an imbalance between…
Synergistic Interactions of Cannabidiol with Chemotherapeutic Drugs in MCF7 Cells: Mode of Interaction and Proteomics Analysis of Mechanisms
Abstract Cannabidiol (CBD), a nonpsychoactive phytocannabinoid, has recently emerged as a potential cytotoxic agent in addition to its ameliorative activity…
Disease-Dependent Antiapoptotic Effects of Cannabidiol for Keratinocytes Observed upon UV Irradiation
Abstract Although apoptosis of keratinocytes has been relatively well studied, there is a lack of information comparing potentially proapoptotic treatments…