Exercise-induced IL-15 acted as a positive prognostic implication and tumor-suppressed role in pan-cancer
Abstract Objective: Exercise can produce a large number of cytokines that may benefit cancer patients, including Interleukin 15 (IL-15). IL-15…
anti-tumor immune response
Regulation, genomics, and clinical characteristics of cuproptosis regulators in pan-cancer
Abstract Background: Cuproptosis, a copper-dependent controlled cell death, is a novel form of cell death that differs from known cell…
Pan-cancer analysis supports MAPK12 as a potential prognostic and immunotherapeutic target in multiple tumor types, including in THCA
Abstract P38 mitogen-activated protein kinase (MAPK)12 (also known as P38 γ) is critical in the development and progression of various…
The role of TGR5 as an onco-immunological biomarker in tumor staging and prognosis by encompassing the tumor microenvironment
Abstract The relationship between G protein–coupled bile acid receptor 1 (TGR5, GPBAR1) and, specifically, cancer has been studied in in…
A pan-cancer analysis of copper homeostasis-related gene lipoyltransferase 1: Its potential biological functions and prognosis values
Abstract As a key copper homeostasis-related molecule, lipoyltransferase 1 (LIPT1) is an essential enzyme for the activation of mitochondrial 2-ketoacid…
Pan-cancer genetic analysis of cuproptosis and copper metabolism-related gene set
Abstract Background: A recent paper has revealed a novel cell death pathway, cuproptosis, a programmed cell death based on copper.…
Multi-Omics Analysis of GNL3L Expression, Prognosis, and Immune Value in Pan-Cancer
Abstract Simple Summary: Guanine nucleotide-binding protein-like 3-like (GNL3L) is a novel GTP-binding nucleolar protein. In this study, we analyzed the…
A novel necroptosis-related gene signature associated with immune landscape for predicting the prognosis of papillary thyroid cancer
Abstract Background: Necroptosis, a type of programmed cell death, has been implicated in a variety of cancer-related biological processes. However,…
Prognostic and immunotherapeutic significance of mannose receptor C type II in 33 cancers: An integrated analysis
Abstract Background: The type 2 mannose receptor C (MRC2) is involved in tumor biological processes and plays a new role…
A comprehensively prognostic and immunological analysis of actin-related protein 2/3 complex subunit 5 in pan-cancer and identification in hepatocellular carcinoma
Abstract Background: Actin-related protein 2/3 complex subunit 5 (ARPC5) is one of the members of actin-related protein 2/3 complex and…