Oncogene or tumor suppressor gene: An integrated pan-cancer analysis of NBPF1
Abstract Neuroblastoma breakpoint family, member 1 (NBPF1), appears to be a double-edged sword with regard to its role in carcinogenesis.…
anti-tumor immune response
Integrated pan-cancer analysis of CSMD2 as a potential prognostic, diagnostic, and immune biomarker
Abstract The protein encoded by CUB and Sushi Multiple Domains 2 (CSMD2) is likely involved in regulating the complement cascade…
A comprehensive prognostic and immunological analysis of ephrin family genes in hepatocellular carcinoma
Abstract Background: Ephrins, a series of Eph-associated receptor tyrosine kinase ligands, play an important role in the tumorigenesis and progression…
A pre-vaccine exploratory survey of SARS-CoV-2 humoral immunity among Egyptian general population
Abstract Background: Population-based studies on COVID-19 have important implications for modeling the pandemic and determining vaccination policies. Limited data are…
Differential Effects of D9 Tetrahydrocannabinol (THC)- and Cannabidiol (CBD)-Based Cannabinoid Treatments on Macrophage Immune Function In Vitro and on Gastrointestinal Inflammation in a Murine Model
Abstract Phytocannabinoids possess a wide range of immune regulatory properties, mediated by the endocannabinoid system. Monocyte/macrophage innate immune cells express…
Dietary Parsley Seed Mitigates Methomyl-Induced Impaired Growth Performance, Hemato-Immune Suppression, Oxidative Stress, Hepato-Renal Damage, and Pseudomonas aeruginosa Susceptibility in Oreochromis niloticus
Abstract The present experiment investigated the potential protective role of parsley (Petroselinum crispum) seed meal (PSM) in alleviating methomyl (MET)-adverse…
Characterizing HDAC Pathway Copy Number Variation in Pan-Cancer
Abstract Background: Histone deacetylase (HDAC) plays a crucial role in regulating the expression and activity of a variety of genes…
The Prognostic and Immunotherapeutic Significance of AHSA1 in Pan-Cancer, and Its Relationship With the Proliferation and Metastasis of Hepatocellular Carcinoma
Abstract The AHSA1 is a main activator of ATPase of Hsp90. Hsp90 is involved in various metabolic and developmental processes…
Transcriptomic Characteristics Associated With Aging in the Thyroid Gland
Abstract The aging thyroid is associated with a plethora of morphological and functional changes. Limited studies have addressed the gene…
SYNJ2 is a novel and potential biomarker for the prediction and treatment of cancers: from lung squamous cell carcinoma to pan-cancer
Abstract Background: The roles and clinical values of synaptojanin 2 (SYNJ2) in lung squamous cell carcinoma (LUSC) remain unclear. Methods:…