NOTCH3 as a prognostic biomarker and its correlation with immune infiltration in gastrointestinal cancers
Abstract NOTCH receptor 3 (NOTCH3) is known to regulate the transcription of oncogenes or tumor suppressor genes, thereby playing a…
anti-tumor immune response
Pan-cancer analysis of the TRAF family genes and their correlation with prognosis, TME, immune and drug sensitivity
Abstract Background: Tumor necrosis factor receptor-associated factors family genes play a pivotal role in tumorigenesis and metastasis, functioning as adapters…
Pan-cancer analysis of the disulfidptosis-related gene RPN1 and its potential biological function and prognostic significance in gliomas
Abstract Background: Numerous studies have shown a strong correlation between disulfidptosis and various cancers. However, the expression and function of…
The prognostic value and immunological role of MVP in pan-cancer study
Abstract Major Vault Protein (MVP) has emerged as a potential prognostic and immunological biomarker in various cancer types. This pan-cancer…
Multi-omics pan-cancer study of SPTBN2 and its value as a potential therapeutic target in pancreatic cancer
Abstract SPTBN2 is a protein-coding gene that is closely related to the development of malignant tumors. However, its prognostic value…
Comprehensive analysis indicated that NDE1 is a potential biomarker for pan‐cancer and promotes bladder cancer progression
Abstract Background: The nuclear distribution E homologue 1 (NDE1) is a crucial dynein binding partner. The NDE1 protein has the…
A comprehensive analysis of the prognostic and immunological role of ANK3 in pan-cancer
Abstract Background: Cancer is a common cause of death around the world. Immunotherapy plays a significant role in cancer treatment…
Pan-cancer analysis revealed prognosis value and immunological relevance of RAMPs
Abstract Whether receptor activity-modifying proteins (RAMPs) play a key role in human cancer prognosis and immunity remains unknown. We used…
A Comprehensive Pan-cancer Analysis of the Biological Immunomodulatory Function and Clinical Value of CD27
Abstract Background:CD27 is an immunological checkpoint gene, plays a critical function inInhibition or activation of cancer immunity. The CD27/CD27L axis…
PEX13 is a potential immunotherapeutic indicator and prognostic biomarker for various tumors including PAAD
Abstract The peroxisome serves a significant role in the occurrence and development of cancers. Specifically, the peroxisomal biogenesis factor 13…