Systematic analysis reveals a pan-cancer SNHG family signature predicting prognosis and immunotherapy response
Abstract Small nucleolar RNA host genes (SNHGs) are a special family of long non-coding RNAs (lncRNAs), which not only function…
anti-tumor immune response
A comprehensive pan-cancer analysis of CDH5 in immunological response
Abstract Background: Cadherin 5 (CDH5) functions critically in maintaining cell adhesion and integrity of endothelial and vascular cells. The expression…
Pan-cancer analysis and experimental validation identify ndc1 as a potential immunological, prognostic and therapeutic biomarker in pancreatic cancer
Abstract NDC1 is a transmembrane nucleoporin that participates in cell mitosis. In the field of oncology, NDC1 has shown its…
Pan-cancer analysis identified OAS1 as a potential prognostic biomarker for multiple tumor types
Abstract Background: 2’,5’-oligoadenylate synthetase 1 (OAS1), has been reported as a tumor driver gene in breast carcinoma and pancreatic carcinoma.…
Pan-cancer analysis of kinesin family members with potential implications in prognosis and immunological role in human cancer
Abstract Background: Kinesin is a molecular motor for transporting “goods” within cells and plays a key role in many types…
Pan-cancer analysis of the PDE4DIP gene with potential prognostic and immunotherapeutic values in multiple cancers including acute myeloid leukemia
Abstract Phosphodiesterase 4D interacting protein (PDE4DIP) interacts with cAMP-specific phosphodiesterase 4D and its abnormal expression promotes the development of hematological…
Pan-cancer analysis reveals the potential of hyaluronate synthase as therapeutic targets in human tumors
Abstract Hyaluronic acid (HA) is a crucial component of the extracellular matrix, and its level of accumulation is related to…
Identifying the role of NUDCD1 in human tumors from clinical and molecular mechanisms: a study based on comprehensive bioinformatics and experimental validation
Abstract NUDCD1 (NudC domain-containing 1) is abnormally activated in multiple tumors and has been identified as a cancer antigen. But…
A potential immunotherapeutic and prognostic biomarker for multiple tumors including glioma: SHOX2
Abstract Background: Short stature homeobox 2 (SHOX2) is significant gene in the development and progression of multiple types of tumors.…
CCNE1 is a predictive and immunotherapeutic indicator in various cancers including UCEC: a pan-cancer analysis
Abstract Background: CCNE1 plays an important oncogenic role in several tumors, especially high-stage serous ovarian cancer and endometrial cancer. Nevertheless,…