Endocannabinoid system and skeletal muscle health: Insights from cannabidiol
Abstract The endocannabinoid (EC) system is a complex network comprising endogenous ligands, enzymes responsible for their synthesis and degradation, and…
anorexia and cachexia
Multifaced roles of cannabinoid therapy in cancer: balancing analgesia, antitumor potential, and systemic toxicity
Abstract Introduction: Cannabinoids hold promise in oncology for symptom relief and antitumor effects, though concerns about safety and efficacy persist.…
Cannabinoids in the treatment of cancer anorexia and cachexia: Where have we been, where are we going?
Abstract Cachexia–anorexia cancer syndrome remains an unmet clinical need with a dearth of treatment and no standard of care. Acting…
Should oncologists trust cannabinoids?
Abstract Cannabis enjoyed a “golden age” as a medicinal product in the late 19th, early 20th century, but the increased…
Managing Cachexia in Head and Neck Cancer: a Systematic Scoping Review
Abstract Introduction: Patients with head and neck cancer (HNC) are usually confronted with functional changes due to the malignancy itself…
Cannabinoid interventions for improving cachexia outcomes in cancer: a systematic review and meta‐analysis
Abstract Cancer‐associated cachexia (CAC) is a wasting syndrome characterized by involuntary weight loss and anorexia. Clear definition and diagnostic criteria…
The Effects of Dosage-Controlled Cannabis Capsules on Cancer-Related Cachexia and Anorexia Syndrome in Advanced Cancer Patients: Pilot Study
Abstract Background: Cancer-related cachexia and anorexia syndrome (CACS) is a common phenomenon in cancer patients. Cannabis has been suggested to…
Chemotherapy‐induced cachexia dysregulates hypothalamic and systemic lipoamines and is attenuated by cannabigerol
Abstract Background: Muscle wasting, anorexia, and metabolic dysregulation are common side‐effects of cytotoxic chemotherapy, having a dose‐limiting effect on treatment…
Pancreas Cancer‐Associated Weight Loss
Abstract This review highlights the etiology, assessment, and management of unintentional weight loss in patients with pancreatic cancer and provides…
Cannabigerol is a novel, well-tolerated appetite stimulant in pre-satiated rats
Abstract Rationale: The appetite-stimulating properties of cannabis are well documented and have been predominantly attributed to the hyperphagic activity of…