Vaping Synthetic Cannabinoids: A Novel Preclinical Model of E-Cigarette Use in Mice
Abstract Smoking is the most common route of administration for cannabis; however, vaping cannabis extracts and synthetic cannabinoids (“fake marijuana”)…
animal models
Evidences for the Anti-panic Actions of Cannabidiol
Abstract BACKGROUND: Panic disorder (PD) is a disabling psychiatry condition that affects approximately 5% of the worldwide population. Currently, long-term…
Cannabidiol as a Potential New Type of an Antipsychotic. A Critical Review of the Evidence
Abstract There is urgent need for the development of mechanistically different and less side-effect prone antipsychotic compounds. The endocannabinoid system…
Cannabidiol, among Other Cannabinoid Drugs, Modulates Prepulse Inhibition of Startle in the SHR Animal Model: Implications for Schizophrenia Pharmacotherapy
Abstract Schizophrenia is a severe psychiatric disorder that involves positive, negative and cognitive symptoms. Prepulse inhibition of startle reflex (PPI)…
Sex-Dependent Vulnerability to Cannabis Abuse in Adolescence
Abstract The goal of this review is to summarize current evidence for sex differences in the response to cannabinoid compounds,…
Effects of Endocannabinoid System Modulation on Cognitive and Emotional Behavior
Abstract Cannabis has long been known to produce cognitive and emotional effects. Research has shown that cannabinoid drugs produce these…
Hippocampal CB1 receptors mediate the memory impairing effects of Δ9-tetrahydrocannabinol
Abstract It is firmly established that the hippocampus, a brain region implicated in spatial learning, episodic memory, and consolidation, contains…