Cannabidiol as a possible treatment for endometriosis through suppression of inflammation and angiogenesis
Abstract Background: Endometriosis is associated with a wide variety of signs and symptoms and can lead to infertility, embryo death,…
Angiogenesis
Antitumor Effects of Cannabis sativa Bioactive Compounds on Colorectal Carcinogenesis
Abstract Cannabis sativa is a multipurpose plant that has been used in medicine for centuries. Recently, considerable research has focused…
Ion Channels in Gliomas—From Molecular Basis to Treatment
Abstract Ion channels provide the basis for the nervous system’s intrinsic electrical activity. Neuronal excitability is a characteristic property of…
Endothelial dysfunction and angiogenesis: what is missing from COVID-19 and cannabidiol story?
Abstract Background: Among pathways involved in the pathogenesis of coronavirus disease 2019 (COVID-19), impaired endothelial cell (EC) function and angiogenesis…
The Interplay between the Immune and the Endocannabinoid Systems in Cancer
Abstract The therapeutic potential of Cannabis sativa has been recognized since ancient times. Phytocannabinoids, endocannabinoids and synthetic cannabinoids activate two…
Molecular Mechanism of Cannabinoids in Cancer Progression
Abstract Cannabinoids are a family of heterogeneous compounds that mostly interact with receptors eliciting several physiological effects both in the…
Collagen-binding vascular endothelial growth factor attenuates CCl4-induced liver fibrosis in mice
Abstract Vascular endothelial growth factor (VEGF) serves an important role in promoting angiogenesis and tissue regeneration. However, the lack of…
The grass isn’t always greener: The effects of cannabis on embryological development
Abstract With the increasing publicity of marijuana due to recent legislation, it is pertinent that the effects of fetal exposure…
Endocannabinoids as Guardians of Metastasis
Abstract Endocannabinoids including anandamide and 2-arachidonoylglycerol are involved in cancer pathophysiology in several ways, including tumor growth and progression, peritumoral…