Abstract Phytocannabinoids possess a wide range of immune regulatory properties, mediated by the endocannabinoid system. Monocyte/macrophage innate immune cells express…
Abstract Background: Glioma is the most common cancer in the central nervous system, and low grade gliomas are notorious for…
Abstract Background: JMJD8 has recently been identified as a cancer-related gene, but current studies provide limited information. We aimed to…
Abstract Cannabinoids, mainly cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC), are the most studied group of compounds obtained from Cannabis sativa because…
Abstract VSIR is a critical immunomodulatory receptor that inhibits T cell effector function and maintains peripheral tolerance. However, the mechanism…
Abstract CD147 plays an important role in promoting tumor proliferation and inhibiting cancer cell apoptosis in the tumor microenvironment. However,…
Abstract The SIRPαFc fusion protein can block the immunosuppressive CD47-SIRPα signal between macrophages and tumor cells as a decoy receptor…
Abstract Macrophages are some of the most important immune cells in the organism and are responsible for creating an inflammatory…
Abstract Background: Colon adenocarcinoma (COAD) is a common digestive system tumor in the world. However, the role and function of…
Abstract Objective: Prolyl 4-hydroxylase, alpha polypeptide I (P4HA1), a key enzyme in collagen synthesis, comprises two identical alpha subunits and…