Abstract Medicine continues to struggle in its approaches to numerous common subjective pain syndromes that lack objective signs and remain…
Abstract The therapeutic properties of cannabinoids have been well demonstrated but are overshadowed by such adverse effects as cognitive and…
Abstract Chemotherapy-induced nausea is one of the most distressing symptoms reported by patients undergoing treatment, and even with the introduction…
Abstract Endocannabinoids including anandamide and 2-arachidonoylglycerol are involved in cancer pathophysiology in several ways, including tumor growth and progression, peritumoral…
Abstract Atherosclerosis is responsible for most cardiovascular disease (CVD) and is caused by several factors including hypertension, hypercholesterolemia, and chronic…
Abstract Background: The endocannabinoid (eCB) system, an endogenous lipid signaling system, appears to be dysregulated in depression. The role of…
Abstract Depression and pain are two of the most debilitating disorders worldwide and have an estimated cooccurrence of up to…
Abstract Endocannabinoids are lipid mediators able to bind to and activate cannabinoid receptors, the primary molecular targets responsible for the…
Abstract Since the first reports in 2001, great advances have been made towards the understanding of endocannabinoid-mediated synaptic modulation. Electrophysiological…
Abstract The endocannabinoid system is a component of the neuroprotective mechanisms that an organism displays after traumatic brain injury (TBI).…