Nucleus Accumbens Associated Protein 1 in Cancers—The Real Value
Abstract Malignant tumors are a leading cause of death worldwide, second only to cardiovascular disease. They occur in every population…
Agricultural genetics
Prenatal cannabis exposure is associated with alterations in offspring DNA methylation at genes involved in neurodevelopment, across the life course
Abstract Prenatal cannabis exposure (PCE) is of increasing concern globally, due to the potential impact on offspring neurodevelopment, and its…
Molecular characteristics and oncogenic role of CHD family genes: a pan-cancer analysis based on bioinformatic and biological analysis
Abstract Chromodomain helicase DNA-binding protein (CHD) gene family, an ATP (adenosine triphosphate) -dependent chromatin remodeler family, is involved in multiple…
WNT5A in Cancer: A Pan-Cancer Analysis Revealing Its Diagnostic and Prognostic Biomarker Potential
Abstract Background and objective: The wingless-related integration site family (WNT) signaling pathway is critical for tumor progression and development. It…
Genetic insights into agronomic and morphological traits of drug-type cannabis revealed by genome-wide association studies
Abstract Cannabis sativa L., previously concealed by prohibition, is now a versatile and promising plant, thanks to recent legalization, opening…
Pan-cancer analysis reveals IL32 is a potential prognostic and immunotherapeutic biomarker in cancer
Abstract Interleukin 32 (IL32) is a pro-inflammatory cytokine that plays a key role in promoting sterile inflammation by modulating immune…
Genetic influences and causal pathways shared between cannabis use disorder and other substance use traits
Abstract Cannabis use disorder (CanUD) has increased with the legalization of the use of cannabis. Around 20% of individuals using…
CDK12 is a potential biomarker for diagnosis, prognosis and immunomodulation in pan-cancer
Abstract Cell cycle-dependent protein kinase 12 (CDK12) plays a key role in a variety of carcinogenesis processes and represents a…
Pan-cancer analysis reveals potential immunological and prognostic roles of METTL7A in human cancers
Abstract Methyltransferase-like protein 7A (METTL7A) is an m6A RNA methyltransferase that has been linked to cancer prognosis and drug resistance.…
Comprehensive analysis of the potential biological significance of cuproptosis-related gene LIPT2 in pan-cancer prognosis and immunotherapy
Abstract Lipoyltransferase 2 (LIPT2) acts as a key enzyme involved in fatty acid metabolism and cell membrane synthesis. However, the…