Pancancer analysis of the correlations of HS6ST2 with prognosis, tumor immunity, and drug resistance
Abstract HS6ST2 has ability to encodes a member of the heparan sulfate (HS) sulfotransferase gene family, which catalyze the transfer…
Agricultural genetics
Establishment of a novel indicator of pyroptosis regulated gene transcription level and its application in pan-cancer
Abstract Pyroptosis is a type of programmed cell death and plays a dual role in distinct cancers. It is elusive…
Pan-cancer analysis of whole-genome doubling and its association with patient prognosis
Abstract Background: Whole-genome doubling (WGD) is a common mutation in cancer. Various studies have suggested that WGD is associated with…
Genome-wide DNA methylation association study of recent and cumulative marijuana use in middle aged adults
Abstract Marijuana is a widely used psychoactive substance in the US and medical and recreational legalization has risen over the…
The value of EYA1/3/4 in clear cell renal cell carcinoma: a study from multiple databases
Abstract There is evidence from multiple studies that dysregulation of the Eyes Absent (EYA) protein plays multiple roles in many…
Distinct dosage compensations of ploidy-sensitive and -insensitive X chromosome genes during development and in diseases
Abstract The active X chromosome in mammals is upregulated to balance its dosage to autosomes during evolution. However, it is…
Human olfactory discrimination of genetic variation within Cannabis strains
Abstract Cannabis sativa L. is grown and marketed under a large number of named strains. Strains are often associated with…
DNA-mediated proteolysis by neutrophil elastase enhances binding activities of the HMGB1 protein
Abstract Neutrophil extracellular traps (NETs) are produced through ejection of genomic DNA by neutrophils into extracellular space and serve as…
A comprehensive analysis of gasdermin family gene as therapeutic targets in pan-cancer
Abstract Six members of the gasdermin family are involved in various biological functions in malignant tumors. The present study aimed…
Role of CD68 in tumor immunity and prognosis prediction in pan-cancer
Abstract CD68 plays a critical role in promoting phagocytosis; however, the function of CD68 in tumor immunity and prognosis remains…