Cannabidiol, a Strategy in Aging to Improve Redox State and Immunity in Male Rats
Abstract Aging is characterized by oxidative stress and immune function impairment, and is associated with increased morbidity. Cannabidiol (CBD) has…
aging adults
Cumulative Deleterious Effects of Tetrahydrocannabinoid (THC) and Ethanol on Mitochondrial Respiration and Reactive Oxygen Species Production Are Enhanced in Old Isolated Cardiac Mitochondria
Abstract Delta 9 tetrahydrocannabinol (THC), the main component of cannabis, has adverse effects on the cardiovascular system, but whether concomitant…
Protective Actions of Cannabidiol on Aging-Related Inflammation, Oxidative Stress and Apoptosis Alterations in Liver and Lung of Long Evans Rats
Abstract Background: Aging is characterised by the progressive accumulation of oxidative damage which leads to inflammation and apoptosis in cells.…
Hippocampal differential expression underlying the neuroprotective effect of delta-9-tetrahydrocannabinol microdose on old mice
Abstract Delta-9-tetrahydrocannabinol (THC) is the primary psychoactive compound of the cannabis plant and an exogenous ligand of the endocannabinoid system.…
Cannabidiol induces autophagy and improves neuronal health associated with SIRT1 mediated longevity
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s11357-022-00559-7. Article type: Research Article Keywords: Cannabidiol, Aging, Autophagy,…
Efficacy of Δ9 -Tetrahydrocannabinol (THC) Alone or in Combination With a 1:1 Ratio of Cannabidiol (CBD) in Reversing the Spatial Learning Deficits in Old Mice
Abstract Decline in cognitive performance, an aspect of the normal aging process, is influenced by the endocannabinoid system (ECS). Cannabinoid…
Are the Acute Effects of THC Different in Aging Adults?
Abstract In recent years of expanding legalization, older adults have reported the largest increase in cannabis use of any age…