Treating Hyperexcitability in Human Cerebral Organoids Resulting from Oxygen-Glucose Deprivation
Abstract Human cerebral organoids resemble the 3D complexity of the human brain and have the potential to augment current drug…
aged brain
Transcriptional Alterations Induced by Delta-9 Tetrahydrocannabinol in the Brain and Gonads of Adult Medaka
Abstract With the legalization of marijuana smoking in several states of the United States and many other countries for medicinal…
An fMRI analysis of verbal and non-verbal working memory in people with a past history of opioid dependence
Abstract Introduction: Working memory describes the ability to maintain and manipulate information held in mind, and it is a fundamental…
Enhancing axonal myelination in seniors: A review exploring the potential impact cannabis has on myelination in the aged brain
Abstract Consumption of cannabis is on the rise as public opinion trends toward acceptance and its consequent legalization. Specifically, the…
Does Bacillus thuringiensis Affect the Stress and Immune Responses of Rhynchophorus ferrugineus Larvae, Females, and Males in the Same Way?
Abstract Simple Summary: Rhynchophorus ferrugineus is a destructive quarantine pest of palm trees, now widely distributed. Although broad-spectrum insecticides are…
Obesity as a Condition Determined by Food Addiction: Should Brain Endocannabinoid System Alterations Be the Cause and Its Modulation the Solution?
Abstract Obesity is a complex disorder, and the number of people affected is growing every day. In recent years, research…
Patterns of brain function associated with cannabis cue-reactivity in regular cannabis users: a systematic review of fMRI studies
Abstract Rationale: Regular cannabis use (i.e. ≥ monthly) is highly prevalent, with past year use being reported by ~ 200…
Cannabis sativa and/or melatonin do not alter brain lipid but alter oxidative mechanisms in female rats
Abstract Background: Lipid profile and redox status play a role in brain (dys)functions. Cannabinoid and melatonergic systems operate in the…
Miswiring the brain: Human prenatal Δ9-tetrahydrocannabinol use associated with altered fetal hippocampal brain network connectivity
Abstract Increasing evidence supports a link between maternal prenatal cannabis use and altered neural and physiological development of the child.…
Development of [18F]LU14 for PET Imaging of Cannabinoid Receptor Type 2 in the Brain
Abstract Cannabinoid receptors type 2 (CB2R) represent an attractive therapeutic target for neurodegenerative diseases and cancer. Aiming at the development…