An fMRI analysis of verbal and non-verbal working memory in people with a past history of opioid dependence
Abstract Introduction: Working memory describes the ability to maintain and manipulate information held in mind, and it is a fundamental…
aged brain
Enhancing axonal myelination in seniors: A review exploring the potential impact cannabis has on myelination in the aged brain
Abstract Consumption of cannabis is on the rise as public opinion trends toward acceptance and its consequent legalization. Specifically, the…
Obesity as a Condition Determined by Food Addiction: Should Brain Endocannabinoid System Alterations Be the Cause and Its Modulation the Solution?
Abstract Obesity is a complex disorder, and the number of people affected is growing every day. In recent years, research…
Patterns of brain function associated with cannabis cue-reactivity in regular cannabis users: a systematic review of fMRI studies
Abstract Rationale: Regular cannabis use (i.e. ≥ monthly) is highly prevalent, with past year use being reported by ~ 200…
Cannabis sativa and/or melatonin do not alter brain lipid but alter oxidative mechanisms in female rats
Abstract Background: Lipid profile and redox status play a role in brain (dys)functions. Cannabinoid and melatonergic systems operate in the…
Miswiring the brain: Human prenatal Δ9-tetrahydrocannabinol use associated with altered fetal hippocampal brain network connectivity
Abstract Increasing evidence supports a link between maternal prenatal cannabis use and altered neural and physiological development of the child.…
Development of [18F]LU14 for PET Imaging of Cannabinoid Receptor Type 2 in the Brain
Abstract Cannabinoid receptors type 2 (CB2R) represent an attractive therapeutic target for neurodegenerative diseases and cancer. Aiming at the development…
Heavy cannabis use, dependence and the brain: a clinical perspective
Abstract Aims: To summarize and evaluate our knowledge of the relationship between heavy cannabis use, cannabis use disorder (CUD) and…
Age-related differences in the impact of cannabis use on the brain and cognition: a systematic review
Abstract Electronic supplementary material: The online version of this article (10.1007/s00406-019-00981-7) contains supplementary material, which is available to authorized users.…
Effects of chronic Δ9-tetrahydrocannabinol treatment on Rho/Rho-kinase signalization pathway in mouse brain
Abstract Δ9-Tetrahydrocannabinol (Δ9-THC) shows its effects by activating cannabinoid receptors which are on some tissues and neurons. Cannabinoid systems have…