Heavy cannabis use, dependence and the brain: a clinical perspective
Abstract Aims: To summarize and evaluate our knowledge of the relationship between heavy cannabis use, cannabis use disorder (CUD) and…
aged brain
Age-related differences in the impact of cannabis use on the brain and cognition: a systematic review
Abstract Electronic supplementary material: The online version of this article (10.1007/s00406-019-00981-7) contains supplementary material, which is available to authorized users.…
Effects of chronic Δ9-tetrahydrocannabinol treatment on Rho/Rho-kinase signalization pathway in mouse brain
Abstract Δ9-Tetrahydrocannabinol (Δ9-THC) shows its effects by activating cannabinoid receptors which are on some tissues and neurons. Cannabinoid systems have…
Biased Agonism of Three Different Cannabinoid Receptor Agonists in Mouse Brain Cortex
Abstract Cannabinoid receptors are able to couple to different families of G proteins when activated by an agonist drug. It…
Cortical thickness in adolescent marijuana and alcohol users: A three-year prospective study from adolescence to young adulthood
Abstract . Adolescent marijuana and alcohol users show thicker cortices compared to controls. More cumulative marijuana use is associated with…
Amygdala activity contributes to the dissociative effect of cannabis on pain perception
Abstract fMRI evidence suggests that delta-9-tetrahydrocannabinol, the psychoactive component of cannabis, targets the affective aspects of pain in humans by…
Shared Mechanisms of Alcohol and Other Drugs
Abstract Identifying the changes that occur in the brain as a result of alcohol and other drug (AOD) use is…