NSUN6 expression correlates with prognosis and immune infiltration in human cancers based on pan-cancer analysis
Abstract NSUN6 is a regulator of tRNA methylation that partially exists in the Golgi and centrosomes. It catalyzes the methylation…
Advanced cancer
NOX4 serves as a pan-cancer prognostic biomarker and therapeutic target in tumorigenesis
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-09690-9. Article type: Research Article Keywords: NADPH oxidase 4,…
Safety, Efficacy and Doxorubicin Pharmacokinetics During Cannabidiol/Cannabidiolic Acid Rich Hemp Oil Use in Dogs With Lymphoma Undergoing CHOP Chemotherapy
Abstract Background: The safety of oral cannabidiol (CBD) and cannabidiolic acid (CBDA)‐rich hemp oil supplementation in dogs with cancer receiving…
Prognostic and immunotherapeutic significance of NCAPD2 in pan-cancer and its role in hepatocellular carcinoma progression via the AKT/GSK-3β signaling pathway
Abstract Present studies indicated that NCAPD2 (Non-SMC condensin I complex subunit D2) has emerged as an essential participant of condensin…
Prevalence and impact of molecular variation in the three-prime repair exonuclease 1 TREX1 and its implications for oncology
Abstract Background: The three-prime repair exonuclease 1, TREX1, degrades cytosolic DNA to prevent aberrant immune activation. Its inactivation results in…
Bioinformatic Analysis of C1GALT1 in Cancer: Insights Into Prognosis, Metastasis and Therapeutic Potential
Abstract Background: This study evaluates the expression, regulation, and clinical relevance of C1GALT1, a key enzyme in mucin‐type O‐glycosylation, across…
PABPN1 as a pan-cancer biomarker: prognostic significance and association with tumor immune microenvironment
Abstract Objective: This study aimed to investigate the role of poly(A) binding protein nuclear 1 (PABPN1) as a potential pan-cancer…
Phytochemicals in Cancer Therapy: A Structured Review of Mechanisms, Challenges, and Progress in Personalized Treatment
Abstract Cancer is a major global health concern. Therefore, new treatment options are needed. The phytochemicals have different chemical structures.…
Cannabis use disorder and severe sepsis outcomes in cancer patients: Insights from a national inpatient sample
Abstract BACKGROUND: The burden of cannabis use disorder (CUD) in the context of its prevalence and subsequent cardiopulmonary outcomes among…
Revealing the therapeutic potential of synthetic cannabinoids: a systematic review of cannabinoid receptor binding dynamics and their implications for cancer therapy
Abstract Background: Cancer remains a major global health issue, prompting the need for innovative treatment approaches that extend beyond conventional…