Cullin-5 (CUL5) as a potential prognostic marker in a pan-cancer analysis of human tumors
Abstract There is some evidence supporting an association between Cullin-5 (CUL5) and cancer, but no research using pan-cancer analysis has…
Advanced cancer
The Pathophysiology and the Therapeutic Potential of Cannabinoids in Prostate Cancer
Abstract Simple Summary: Prostate cancer, after lung cancer, is the leading cause of death among men. The incidence rate of…
Cannabidiol Induces Apoptosis and Perturbs Mitochondrial Function in Human and Canine Glioma Cells
Abstract Cannabidiol (CBD), the major non-psychoactive compound found in cannabis, is frequently used both as a nutraceutical and therapeutic. Despite…
Plants Used for the Traditional Management of Cancer in the Eastern Cape Province of South Africa: A Review of Ethnobotanical Surveys, Ethnopharmacological Studies and Active Phytochemicals
Abstract Cancer occurrence is rapidly increasing all over the world, including in developing countries. The current trend in cancer management…
Cannabis Use among Cancer Survivors amid the COVID-19 Pandemic: Results from the COVID-19 Cannabis Health Study
Abstract Simple Summary: During the COVID-19 pandemic, cancer survivors have been identified as a population with an increased risk for…
Clinical significance of P-class pumps in cancer
Abstract P-class pumps are specific ion transporters involved in maintaining intracellular/extracellular ion homeostasis, gene transcription, and cell proliferation and migration…
A pancancer overview of FBN1, asprosin and its cognate receptor OR4M1 with detailed expression profiling in ovarian cancer
Abstract Ovarian cancer affects >295,000 women worldwide and is the most lethal of gynaecological malignancies. Often diagnosed at a late…
Epidemiological overview of multidimensional chromosomal and genome toxicity of cannabis exposure in congenital anomalies and cancer development
Abstract Cannabis and cannabinoids are implicated in multiple genotoxic, epigenotoxic and chromosomal-toxic mechanisms and interact with several morphogenic pathways, likely…
Long-term cancer survival prediction using multimodal deep learning
Abstract The age of precision medicine demands powerful computational techniques to handle high-dimensional patient data. We present MultiSurv, a multimodal…
Pan-cancer chromatin analysis of the human vtRNA genes uncovers their association with cancer biology
Abstract Background: The vault RNAs (vtRNAs) are a class of 84-141-nt eukaryotic non-coding RNAs transcribed by RNA polymerase III, associated…