Pan-caner analysis identifies PSMA7 as a targets for amplification at 20q13.33 in tumorigenesis
Abstract The chromosome 20 long arm (20q) is one of the genomic hotspots where copy number alterations frequently occur in…
Advanced cancer
Systematic pan-cancer analyses of the potential function of the Golgi scaffold protein PAQR3
Abstract Progesterone and AdipoQ Receptor 3 (PAQR3) is a member of the AdipoQ receptor. Our previous studies have found that…
Death-associated protein 3 in cancer—discrepant roles of DAP3 in tumours and molecular mechanisms
Abstract Cancer, ranks as the secondary cause of death, is a group of diseases that are characterized by uncontrolled tumor…
A pancancer analysis of the clinical and genomic characteristics of multiple primary cancers
Abstract Multiple primary cancer (MPC) denotes individuals with two or more malignant tumors occurring simultaneously or successively. Herein, a total…
Single-cell transcriptomics reveals the role of antigen presentation in liver metastatic breast cancer
Abstract Liver metastasis (LM) is the primary cause of cancer-related mortality in late-stage breast cancer (BC) patients. Here we report…
Buds and Bugs: A Fascinating Tale of Gut Microbiota and Cannabis in the Fight against Cancer
Abstract Emerging research has revealed a complex bidirectional interaction between the gut microbiome and cannabis. Preclinical studies have demonstrated that…
Prognostic value of mitochondrial CKMT2 in Pan-cancer and its tumor immune correlation analysis
Abstract Mitochondrial metabolism has been shown to play a key role in immune cell survival and function, but mitochondrial creatine…
Fibroblast activation protein (FAP) as a prognostic biomarker in multiple tumors and its therapeutic potential in head and neck squamous cell carcinoma
Abstract Background: Fibroblast activation protein (FAP), a cell surface serine protease, plays roles in tumor invasion and immune regulation. However,…
Comprehensive analysis of the potential biological significance of cuproptosis-related gene LIPT2 in pan-cancer prognosis and immunotherapy
Abstract Lipoyltransferase 2 (LIPT2) acts as a key enzyme involved in fatty acid metabolism and cell membrane synthesis. However, the…
Cannabinoids in Treating Chemotherapy-Induced Nausea and Vomiting, Cancer-Associated Pain, and Tumor Growth
Abstract Cannabis has been used as an herbal remedy for thousands of years, and recent research indicates promising new uses…