Comprehensive Pan-Cancer Analysis of Senescence With Cancer Prognosis and Immunotherapy
Abstract Senescence is a double-edged sword in tumorigenesis and affects the immunotherapy response through the modulation of the host’s immune…
adoptive cellular immunotherapy
AP3S1 is a Novel Prognostic Biomarker and Correlated With an Immunosuppressive Tumor Microenvironment in Pan-Cancer
Abstract Background: Adaptor-related protein complex 3, sigma one subunit (AP3S1) is one of the encoding subunits of the adaptor complex…
Comprehensive Landscape of RRM2 with Immune Infiltration in Pan-Cancer
Abstract Simple Summary: RRM2 is a crucial subunit of ribonucleotide reductase. In this article, we provided a comprehensive analysis of…
SQLE, A Key Enzyme in Cholesterol Metabolism, Correlates With Tumor Immune Infiltration and Immunotherapy Outcome of Pancreatic Adenocarcinoma
Abstract Background: Pancreatic adenocarcinoma (PAAD) is a treatment-refractory cancer with poor prognosis. Accumulating evidence suggests that squalene epoxidase (SQLE) plays…
KIF2C is a Biomarker Correlated With Prognosis and Immunosuppressive Microenvironment in Human Tumors
Abstract Kinesin superfamily member 2C (KIF2C) is an essential regulator of the cell cycle and its aberrant expression can promote…
A Pan-Cancer Analysis of IRAK1 Expression and Their Association With Immunotherapy Response
Abstract IRAK1 is an active kinase which plays a critical role in IL-1/TLR signaling pathway involved in inflammation and innate…
APOBEC-mediated mutagenesis is a favorable predictor of prognosis and immunotherapy for bladder cancer patients: evidence from pan-cancer analysis and multiple databases
Abstract Background: The APOBEC (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like) family-mediated mutagenesis is widespread in human cancers. However, our…
Pan-Cancer Analysis of the Oncogenic and Immunological Role of RCN3: A Potential Biomarker for Prognosis and Immunotherapy
Abstract Despite emerging publications have elucidated a functional association between RCN3 and tumors, no evidence about a pan-cancer analysis of…
Pan-Cancer Analysis of the Characteristics of LY96 in Prognosis and Immunotherapy Across Human Cancer
Abstract Lymphocyte antigen 96 (LY96) is implicated in tumorigenesis by modulating host immunity. However, an integrated pan-cancer analysis of LY96…
SOCS3 Acts as an Onco-immunological Biomarker With Value in Assessing the Tumor Microenvironment, Pathological Staging, Histological Subtypes, Therapeutic Effect, and Prognoses of Several Types of Cancer
Abstract The suppressor of cytokine signaling (SOCS) family contains eight members, including SOCS1–7 and CIS, and SOCS3 has been shown…