Cannabidiol Enhances SIRT1 and Autophagy for the Maintenance of Human Mesenchymal Stem Cells
Abstract Background/Aim: Mesenchymal stem cells (MSCs) are used to treat various degenerative diseases. However, their therapeutic potential is limited by…
adipose tissue-derived mesenchymal stem cells
Integrated Analysis of Clinical Outcome of Mesenchymal Stem Cell-related Genes in Pan-cancer
Abstract Background: Although the application of mesenchymal stem cells (MSCs) in engineered medicine, such as tissue regeneration, is well known,…
Distinct roles of ADIPOR1 and ADIPOR2: A pan-cancer analysis
Abstract Introduction: AdipoR1 and AdipoR2 proteins, encoded by ADIPOR1 and ADIPOR2 genes respectively, are the receptors of adiponectin secrected by…
Distinct Effects of Cannabidiol on Sphingolipid Metabolism in Subcutaneous and Visceral Adipose Tissues Derived from High-Fat-Diet-Fed Male Wistar Rats
Abstract Available data suggest that cannabidiol (CBD) may ameliorate symptoms of insulin resistance by modulating the sphingolipid concentrations in particular…
HIF3A Inhibition Triggers Browning of White Adipocytes via Metabolic Rewiring
Abstract Maintenance of energy balance between intake and expenditure is a prerequisite of human health, disrupted in severe metabolic diseases,…
Cannabinoid-Induced Autophagy and Heme Oxygenase-1 Determine the Fate of Adipose Tissue-Derived Mesenchymal Stem Cells under Stressful Conditions
Abstract The administration of adipose tissue-derived mesenchymal stem cells (ADMSCs) represents a promising therapeutic option after myocardial ischemia or myocardial…
Cannabis alleviates neuropathic pain and reverses weight loss in diabetic neuropathic cachexia in a previous heroin abuser
Abstract Summary: Ten years after the successful withdrawal from heroin abuse, a person with diabetes suffered intractable pain and severe…
ISOexpresso: a web-based platform for isoform-level expression analysis in human cancer
Abstract Background: Alternative splicing events that result in the production of multiple gene isoforms reveals important molecular mechanisms. Gene isoforms…