Exploring potential anti-inflammatory effects of medicinal cannabis
Abstract Purpose: Inflammation is thought to play a key role in malignant disease and may play a significant part in…
acute inflammation
Cannabinoids in the treatment of cancer anorexia and cachexia: Where have we been, where are we going?
Abstract Cachexia–anorexia cancer syndrome remains an unmet clinical need with a dearth of treatment and no standard of care. Acting…
The Anti-Inflammatory Effects of Cannabis sativa Extracts on LPS-Induced Cytokines Release in Human Macrophages
Abstract Inflammation is the response of the innate immune system to any type of injury. Although acute inflammation is critical…
Cannabidiol-Loaded Nanoparticles Based on Crosslinked Starch: Anti-Inflammatory Activity and Improved Nose-to-Brain Delivery
Abstract Cannabidiol (CBD) has previously been shown to inhibit inflammatory cytokine production in both in vitro and in vivo studies…
Exploring the Therapeutic Potential of Cannabinoid Receptor Antagonists in Inflammation, Diabetes Mellitus, and Obesity
Abstract Recently, research has greatly expanded the knowledge of the endocannabinoid system (ECS) and its involvement in several therapeutic applications.…
Cannabidiol inhibits neuroinflammatory responses and circuit-associated synaptic loss following damage to a songbird vocal pre-motor cortical-like region
Abstract The non-euphorigenic phytocannabinoid cannabidiol (CBD) has been used successfully to treat childhood-onset epilepsies. These conditions are associated with developmental…
Altered endocannabinoidome bioactive lipid levels accompany reduced DNBS-induced colonic inflammation in germ-free mice
Abstract Background: Gut microbiota are involved in the onset and development of chronic intestinal inflammation. The recently described endocannabinoidome (eCBome),…
Anti-inflammatory effects of CBD in human microglial cell line infected with HIV-1
Abstract Human immunodeficiency virus (HIV) infection is associated with a chronic inflammatory stage and continuous activation of inflammasome pathway. We…
Characterization of the biochemical and behavioral effects of cannabidiol: implications for migraine
Abstract Cannabidiol (CBD) is the main pharmacologically active phytocannabinoid. CBD exerts an analgesic effect in several pain models, does not…
Antitumor Effects of Cannabis sativa Bioactive Compounds on Colorectal Carcinogenesis
Abstract Cannabis sativa is a multipurpose plant that has been used in medicine for centuries. Recently, considerable research has focused…