Therapeutic potential of acidic cannabinoids: an update
Abstract Cannabis sativa yields a wide range of bioactive compounds, including terpenes, flavonoids, and cannabinoids. Tetrahydrocannabinolic acid (THCA), cannabidiolic acid…
acute inflammation
Fecal microbiota transplantation to reduce immune activation in ART-treated people with HIV with low CD4/CD8 ratio: protocol for the single-blind, randomized, placebo-controlled Gutsy study (CIHR/CTN PT038)
Abstract Background: Despite antiretroviral therapy (ART) controlling HIV viral replication, people with HIV (PWH) remain at risk for inflammatory non-AIDS…
Biological sex modulates lung injury severity in adolescent mice exposed to short‐term aerosolized vitamin E acetate
Abstract The E‐cigarette or Vaping product‐Associated Lung Injury (EVALI) causes severe acute respiratory failure and, in some cases, death. Most…
Cannabidiol reduces LPS-induced inflammatory response in the human placenta by reducing NF-κB translocation
Abstract Background: Cannabidiol (CBD), a non-psychoactive cannabinoid increasingly used during pregnancy, has been proposed to modulate inflammatory processes. However, its…
Insights into cannabinoid receptor 2 (CB2) anterograde trafficking and pharmacological chaperoning
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00018-025-05961-w. Article type: Research Article Keywords: Receptor, cannabinoid, Cannabinoid…
Effect of Central Injection of Anandamide on LPS-Dependent Suppression of GnRH/LH Secretion in Ewes During the Follicular Phase of the Estrous Cycle
Abstract The study investigated the effects of intracerebroventricular (ICV) administration of the endocannabinoid anandamide (AEA) on suppression of gonadotropin-releasing hormone…
Efficacy of cannabis oil on appetite and quality of life in systemic sclerosis patients: a randomized placebo-controlled trial
Abstract Background: The efficacy of cannabinoids as appetite stimulants in chronic wasting disorders is well established; however, their role in…
Exploring Cannabidiol’s Role in Regenerative Medicine: Focus on Neural and Skeletal Tissues
Abstract Cannabidiol (CBD) is a non-psychotropic compound found in plants of the Cannabis genus, extensively studied for its therapeutic potential.…
Differential Effects of Cannabinoid Receptor 2 Agonists on HIV Replication and Inflammatory Activation in Monocyte-Derived Macrophages and Induced Pluripotent Stem Cell-Derived Microglia
Abstract Graphical Abstract: Created in BioRender. Espinoza, C. (2025) https://BioRender.com/mxfla3i Supplementary Information: The online version contains supplementary material available at…
The Associative Impact of Recreational Cannabis Use on Sinonasal Diseases
Abstract Objective(s): With growing cannabis use in the US, it is crucial to understand the impact of recreational use on…