The CB2 receptor and its role as a regulator of inflammation
Abstract The CB2 receptor is the peripheral receptor for cannabinoids. It is mainly expressed in immune tissues, highlighting the possibility…
acute inflammation
Up-regulation of immunomodulatory effects of mouse bone-marrow derived mesenchymal stem cells by tetrahydrocannabinol pre-treatment involving cannabinoid receptor CB2
Abstract Chronic pain is commonly and closely correlated with inflammation. Both cannabinoid signaling and mesenchymal stem cells (MSCs) have been…
A new formulation of cannabidiol in cream shows therapeutic effects in a mouse model of experimental autoimmune encephalomyelitis
Abstract Background: The present study was designed to investigate the efficacy of a new formulation of alone, purified cannabidiol (CBD)…
Crosstalk between endocannabinoid and immune systems: a potential dysregulation in depression?
Abstract Background: The endocannabinoid (eCB) system, an endogenous lipid signaling system, appears to be dysregulated in depression. The role of…
Evaluation of the role of the cannabidiol system in an animal model of ischemia/reperfusion kidney injury
Abstract Objective: This work aimed to investigate the effects of the administration of cannabidiol in a kidney ischemia/reperfusion animal model.…
Ligand-based virtual screening identifies a family of selective cannabinoid receptor 2 agonists
Keywords: Cannabinoid receptor 2, Cannabinoid receptor 1, Agonist, Inflammation, Ligand-based screening Authors: Matteo Gianella-Borradori, Ivy Christou, Carole J.R. Bataille, Rebecca…
Cannabidiol protects oligodendrocyte progenitor cells from inflammation-induced apoptosis by attenuating endoplasmic reticulum stress
Abstract Cannabidiol (CBD) is the most abundant cannabinoid in Cannabis sativa that has no psychoactive properties. CBD has been approved…
Cannabinoid Modulation of Neuroinflammatory Disorders
Abstract In recent years, a growing interest has been dedicated to the study of the endocannabinoid system. The isolation of…
Systematic review of herbals as potential anti-inflammatory agents: Recent advances, current clinical status and future perspectives
Abstract Many synthetic drugs reported to be used for the treatment of inflammatory disorders are of least interest now a…
Dendritic Cell Regulation by Cannabinoid-Based Drugs
Abstract Cannabinoid pharmacology has made important advances in recent years after the cannabinoid system was discovered. Studies in experimental models…