Cannabinoid Delivery Systems for Pain and Inflammation Treatment
Abstract There is a growing body of evidence to suggest that cannabinoids are beneficial for a range of clinical conditions,…
acute inflammation
Cannabidiol Attenuates Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis Through Induction of Myeloid-Derived Suppressor Cells
Abstract Multiple sclerosis (MS) is a chronic debilitating autoimmune disease without a cure. While the use of marijuana cannabinoids for…
A New Inflammatory Marker: Elevated Monocyte to HDL Cholesterol Ratio Associated with Smoking
Abstract Objectives: The adverse effects of smoking in various pathologies are mediated by its effects on the inflammatory system. The…
The Cannabinoids Δ8THC, CBD, and HU-308 Act via Distinct Receptors to Reduce Corneal Pain and Inflammation
Abstract Background and Purpose: Corneal injury can result in dysfunction of corneal nociceptive signaling and corneal sensitization. Activation of the…
Benefits of VCE-003.2, a cannabigerol quinone derivative, against inflammation-driven neuronal deterioration in experimental Parkinson’s disease: possible involvement of different binding sites at the PPARγ receptor
Abstract Background: Neuroprotection with cannabinoids in Parkinson’s disease (PD) has been afforded predominantly with antioxidant or anti-inflammatory cannabinoids. In the…
Parameters of the Endocannabinoid System as Novel Biomarkers in Sepsis and Septic Shock
Abstract Sepsis represents a dysregulated immune response to infection, with a continuum of severity progressing to septic shock. This dysregulated…
Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis
Abstract The nonpsychoactive cannabis-derivative cannabidiol (CBD) reduced nociceptor activity and pain in end-stage osteoarthritis. Prophylactic treatment with CBD prevented joint…
Cannabis and Myocardial Infarction: Risk Factors and Pathogenetic Insights
Abstract Cannabis use in the US is rising with increased legalization. It has been noted that there is a five-fold…
High Cellular Monocyte Activation in People Living With Human Immunodeficiency Virus on Combination Antiretroviral Therapy and Lifestyle-Matched Controls Is Associated With Greater Inflammation in Cerebrospinal Fluid
Abstract Background: Increased monocyte activation and intestinal damage have been shown to be predictive for the increased morbidity and mortality…
Impact of Cannabis, Cannabinoids, and Endocannabinoids in the Lungs
Abstract Since the identification of cannabinoid receptors in the 1990s, a research field has been dedicated to exploring the role…