Biomarkers of Electronic Nicotine Delivery Systems (ENDS) use
Abstract This perspective summarizes available evidence on biomarkers of exposure in electronic nicotine delivery system (ENDS) users to aid the…
acute human exposure assessment
Prenatal exposure to persistent and non-persistent chemical mixtures and associations with adverse birth outcomes in the Atlanta African American Maternal-Child Cohort
Abstract Background: African Americans (AAs) experience higher rates of preterm birth and fetal growth restriction relative to other pregnant populations.…
Substance Use and Psychological Distress in Mexican Adults during COVID-19 Pandemic: A Cross-Sectional Study
Abstract Objectives: This observational cross-sectional study examined changes in substance use during the coronavirus disease 2019 (COVID-19) pandemic in the…
A First-Tier Framework for Assessing Toxicological Risk from Vaporized Cannabis Concentrates
Abstract Vaporization is an increasingly prevalent means to consume cannabis, but there is little guidance for manufacturers or regulators to…
Osteogenic growth peptide is a potent anti-inflammatory and bone preserving hormone via cannabinoid receptor type 2
Abstract The endocannabinoid system consists mainly of 2-arachidonoylglycerol and anandamide, as well as cannabinoid receptor type 1 and type 2…
Cannabis sativa Extract Induces Apoptosis in Human Pancreatic 3D Cancer Models: Importance of Major Antioxidant Molecules Present Therein
Abstract In recent years, interest in Cannabis sativa L. has been rising, as legislation is moving in the right direction.…
Clinical management of cannabis withdrawal
Abstract Background and Aims: Cannabis withdrawal is a well‐characterized phenomenon that occurs in approximately half of regular and dependent cannabis…
The International Cannabis Toolkit (iCannToolkit): a multidisciplinary expert consensus on minimum standards for measuring cannabis use
Abstract Background: The lack of an agreed international minimum approach to measuring cannabis use hinders the integration of multidisciplinary evidence…
Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace
Abstract The mTORC1 kinase complex regulates cell growth, proliferation, and survival. Because mis-regulation of DEPTOR, an endogenous mTORC1 inhibitor, is…
Cannabidiol and Amisulpride Improve Cognition in Acute Schizophrenia in an Explorative, Double-Blind, Active-Controlled, Randomized Clinical Trial
Abstract Cannabidiol (CBD), a principal phytocannabinoid constituent, has demonstrated antipsychotic properties in recent clinical trials. While it has also been…