Abstract Background: Chronic pain is a significant clinical problem and a very complex pathophysiological phenomenon. There is growing evidence that…
Abstract BACKGROUND: Cannabis is purported to alleviate symptoms related to cancer treatment, although the patterns of use among cancer patients…
Abstract The cannabinoid 1 receptor and cannabinoid 2 receptor can both be targeted in the treatment of pain; yet, they…
Abstract The nonpsychoactive cannabis-derivative cannabidiol (CBD) reduced nociceptor activity and pain in end-stage osteoarthritis. Prophylactic treatment with CBD prevented joint…
Abstract Supplemental Digital Content is Available in the Text. Endocannabinoid signalling within brainstem centres that control top-down pain control changes…
Abstract Background: Pain involves different brain regions and is critically determined by emotional processing. Among other areas, the rostral anterior…
Abstract Background: The use of medical cannabis is increasing, most commonly for pain, anxiety and depression. Emerging data suggest that…
Abstract Introduction: Cannabis has been used for medical purposes across the world for centuries. As states and countries implement medical…
Abstract Cannabinoid (CB) and opioid systems are both involved in analgesia, food intake, mood and behavior. Due to the co-localization…
Abstract Chronic pain is commonly and closely correlated with inflammation. Both cannabinoid signaling and mesenchymal stem cells (MSCs) have been…