Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00018-025-05961-w. Article type: Research Article Keywords: Receptor, cannabinoid, Cannabinoid…
Abstract Nicandrin B (Nic B), a withanolide isolated from Datura ferox leaves, was investigated for its antinociceptive and anti‐inflammatory effects…
Abstract Background: Depression is a prevalent and disabling disorder that poses serious problems in mental health care, and rapid antidepressants…
Abstract Neuropathic pain, a debilitating condition, remains challenging to manage effectively. An insight into neuropharmacological mechanisms is critical for optimizing…
Abstract Preserving the function and survival of pancreatic beta-cells, in order to achieve long-term glycemic control and prevent complications, is…
Abstract For millennia, various cultures have utilized cannabis for food, textile fiber, ethno-medicines, and pharmacotherapy, owing to its medicinal potential…
Abstract Cannabinoids have shown potential in drug-resistant epilepsy treatment; however, we lack knowledge on which cannabinoid(s) to use, dosing, and…
Abstract The endocannabinoid system is widely expressed throughout the body and is comprised of receptors, ligands, and enzymes that maintain…
Abstract The endocannabinoid system is widely expressed throughout the body and is comprised of receptors, ligands, and enzymes that maintain…
Abstract The brain’s ability to strengthen or weaken synaptic connections is often termed synaptic plasticity. It has been shown to…