Cannabidiol Modulates Alterations in PFC microRNAs in a Rat Model of Depression
Abstract Cannabidiol (CBD) is a potential antidepressant agent. We examined the association between the antidepressant effects of CBD and alterations…
5-HT1A receptors
Effects of cannabinoids in Parkinson’s disease animal models: a systematic review and meta-analysis
Abstract Objectives: Cannabis has been proposed as a potential treatment for Parkinson’s disease (PD) due to its neuroprotective benefits. However,…
Distribution of Cannabinoid Receptors in Keratinocytes of Healthy Dogs and Dogs With Atopic Dermatitis
Abstract It is commonly accepted that some form of skin barrier dysfunction is present in canine atopic dermatitis (AD), one…
Effects of Rare Phytocannabinoids on the Endocannabinoid System of Human Keratinocytes
Abstract The decriminalization and legalization of cannabis has paved the way for investigations into the potential of the use of…
Small Molecule Compounds of Natural Origin Target Cellular Receptors to Inhibit Cancer Development and Progression
Abstract Receptors are macromolecules that transmit information regulating cell proliferation, differentiation, migration and apoptosis, play key roles in oncogenic processes…
Neuroprotective Effects of Cannabidiol but Not Δ9-Tetrahydrocannabinol in Rat Hippocampal Slices Exposed to Oxygen-Glucose Deprivation: Studies with Cannabis Extracts and Selected Cannabinoids
Abstract (1) Background: Over the past 10 years, a number of scientific studies have demonstrated the therapeutic potential of cannabinoid…
Fool’s gold: diseased marijuana and cannabis hyperemesis syndrome
Keywords: cannabinoids, receptors, cannabinoid, smoking, emergency service, hospital Authors: Oscar Armando Dorantes ⚬ Affiliations: San Diego State University, San Diego,…
The (Poly)Pharmacology of Cannabidiol in Neurological and Neuropsychiatric Disorders: Molecular Mechanisms and Targets
Abstract Cannabidiol (CBD), the major nonpsychoactive Cannabis constituent, has been proposed for the treatment of a wide panel of neurological…
Topical Treatments and Their Molecular/Cellular Mechanisms in Patients with Peripheral Neuropathic Pain—Narrative Review
Abstract Neuropathic pain in humans results from an injury or disease of the somatosensory nervous system at the peripheral or…
Cannabidiol as a Potential Treatment for Anxiety and Mood Disorders: Molecular Targets and Epigenetic Insights from Preclinical Research
Abstract Cannabidiol (CBD) is the most abundant non-psychoactive component of cannabis; it displays a very low affinity for cannabinoid receptors,…