FibrilPaint to determine the length of Tau amyloids in fluids
Abstract The Tau protein forms amyloid fibrils in diseases like Alzheimer’s. Development of Tau fibrils correlate with disease progression. Until…
Abstract The Tau protein forms amyloid fibrils in diseases like Alzheimer’s. Development of Tau fibrils correlate with disease progression. Until…
Abstract Background: Cannabidiol (CBD), the second most abundant phytocannabinoid in Cannabis sativa, has garnered significant interest due to its non-psychoactive…
Abstract The assembly of tau into filaments defines tauopathies, a group of neurodegenerative diseases including Alzheimer’s disease (AD), Pick’s disease…
Abstract Background: Tauopathies are a group of age-related neurodegenerative diseases characterized by the accumulation of pathologically hyperphosphorylated tau protein in…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s13024-024-00741-9. Article type: Research Article Keywords: Tau, Tauopathies, Mass…
Abstract Background: Tauopathies are a group of age-related neurodegenerative diseases characterized by the accumulation of pathologically phosphorylated tau protein in…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s40478-023-01655-1. Article type: Research Article Keywords: Astrocytes, Stem cells,…
Abstract Astrocytic tau aggregates are seen in several primary and secondary tauopathies, including progressive supranuclear palsy (PSP), corticobasal degeneration (CBD),…
Abstract Background: Tauopathies are a group of neurodegenerative diseases where there is pathologic accumulation of hyperphosphorylated tau protein (ptau). The…
Abstract (1) Background: Prion-like transcellular spreading of tau pathology in Alzheimer’s disease (AD) is mediated by tau binding to the…