ITGAV as a promising diagnostic, immunological, and prognostic biomarker in pan-cancer
Abstract Integrin αV (ITGAV) plays a key role in cell adhesion, migration, and immune regulation, and is implicated in tumor…
Science Article
TRP channels in hepatocellular carcinoma: integrative Mendelian randomization and multi-omics analyses highlight MCOLN3/TRPV4 as candidate dual-effect biomarkers
Abstract Background: The causal relationship between Transient receptor potential (TRP) and hepatocellular carcinoma (HCC) remains unclear. Our study aimed to…
Pharmacological advances in cannabinoid-based therapies for pancreatic cancer: preclinical efficacy of CCL-106 and its epimers
Abstract Background: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive and lethal form of cancer with limited treatment options and poor…
Discontinuation rates and predictors of Medical Cannabis cessation for chronic musculoskeletal pain
Abstract Medical cannabis (MC) is increasingly used as a treatment for chronic musculoskeletal pain, but there is limited data on…
Increased Mesostriatal Intrinsic Connectivity Associated With Cue Exposure in Adult Cannabis Users: Preliminary Findings
Abstract Cue‐induced craving—the desire to use a drug triggered by exposure to cues associated with prior use—is a central mechanism…
Adverse childhood experiences, resilience, and cannabis use in early motherhood
Abstract Background: Exposure to Adverse Childhood Experiences (ACEs) is associated with increased risk of substance use in women, including cannabis…
Single oral administration of dronabinol increases ocular blood flow in patients with glaucoma
Abstract Purpose: Glaucoma is a leading cause of irreversible blindness globally, primarily driven by elevated intraocular pressure (IOP). Still, some…
Liposomal Co-Delivery of Acteoside, CBD, and Naringenin: A Synergistic Strategy Against Gliomas
Abstract Background/Objectives: Adult-type diffuse gliomas, including astrocytoma and glioblastoma multiforme (GBM), are brain tumors with a very poor prognosis. While…
Effect of Plant-Based Proteins on Recovery from Resistance Exercise-Induced Muscle Damage in Healthy Young Adults—A Systematic Review
Abstract Background: Plant-based protein supplementation in supporting muscle recovery following resistance exercise remains an area of growing interest, particularly among…
Consensus based recommendations for the management of post-COVID long-term sequelae (Long COVID): a regional perspective
Abstract Background and objective: The coronavirus disease 2019 (COVID-19) pandemic marks the biggest public health emergency of the 21st century.…