The impact of childhood trauma and cannabis use on paranoia: a structural equation model approach
Abstract Background: Childhood trauma is a well-established risk factor for psychosis, paranoia, and substance use, with cannabis being a modifiable…
Science Article
The Anti-Glioblastoma Effects of Novel Liposomal Formulations Loaded with Cannabidiol, Celecoxib, and 2,5-Dimethylcelecoxib
Abstract Background/Objectives: Glioblastoma multiforme (GBM) therapy efficacy remains limited due to the poor blood-brain barrier-penetrating power of drugs as well…
Molecular profiling and sex determination of Cannabis sativa germplasm collection: Exploring microsatellite markers and high-resolution melting (HRM) analysis
Abstract Cannabis sativa L., a versatile plant grown for its seeds, fiber, and cannabinoids, has recently received significant scientific interest…
Machine learning derived development and validation of extracellular matrix related signature for predicting prognosis in adolescents and young adults glioma
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-13547-6. Article type: Research Article Keywords: Adolescents and young…
Enhancing image retrieval through optimal barcode representation
Abstract Data binary encoding has proven to be a versatile tool for optimizing data processing and memory efficiency in various…
ITGAV as a promising diagnostic, immunological, and prognostic biomarker in pan-cancer
Abstract Integrin αV (ITGAV) plays a key role in cell adhesion, migration, and immune regulation, and is implicated in tumor…
TRP channels in hepatocellular carcinoma: integrative Mendelian randomization and multi-omics analyses highlight MCOLN3/TRPV4 as candidate dual-effect biomarkers
Abstract Background: The causal relationship between Transient receptor potential (TRP) and hepatocellular carcinoma (HCC) remains unclear. Our study aimed to…
Pharmacological advances in cannabinoid-based therapies for pancreatic cancer: preclinical efficacy of CCL-106 and its epimers
Abstract Background: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive and lethal form of cancer with limited treatment options and poor…
Discontinuation rates and predictors of Medical Cannabis cessation for chronic musculoskeletal pain
Abstract Medical cannabis (MC) is increasingly used as a treatment for chronic musculoskeletal pain, but there is limited data on…
Increased Mesostriatal Intrinsic Connectivity Associated With Cue Exposure in Adult Cannabis Users: Preliminary Findings
Abstract Cue‐induced craving—the desire to use a drug triggered by exposure to cues associated with prior use—is a central mechanism…