Cannabidiol in Food and Food Supplements: Drug, Novel Food and Hazard Triangle
Abstract The concept of the “cannabidiol (CBD) Hazard Triangle” reflects the unique position of CBD at the intersection of three…
Science Article
Influence of cannabis potency on mental health outcomes among adolescents and young adults: scoping review
Abstract Background: Recently, there has been a significant rise in potency (% tetrahydrocannabinol (THC)) of cannabis products globally. As such,…
Protocol to prepare inclusion complex-enhanced cannabinoid nano-micelles for behavioral pharmacology and in vivo neurophysiology in mice
Abstract Cannabinoids have significant therapeutic potential but are limited by hydrophobicity and low bioavailability. Here, we present a protocol for…
Effects of anthelmintics and gastrointestinal nematode infection intensity on growth and production performance and carcass quality in western Canadian feedlot cattle
Abstract A randomized controlled trial determined the effects of anthelmintic treatments on growth and production performance, and carcass quality in…
Endocannabinoid system modulation in bruxism: a neurobiological hypothesis and translational model of ECS-targeted intervention
Abstract Bruxism is a multifactorial motor behavior of predominantly central origin, characterized by repetitive masticatory muscle activity and associated with…
Advances in drug addiction research using Caenorhabditis elegans: behavioral and molecular mechanisms
Abstract Drug addiction is a complex, chronic, and relapsing neurological disorder characterized by persistent neuroadaptation and a substantial public health…
The relevance of cannabinoid receptor 2 in the central nervous system: an update over the last 3 years
Abstract The endocannabinoid system is a neuromodulatory network regulating synaptic plasticity, neuronal activity, and neuroinflammatory responses in both the central…
Suspected Cannabinoid Hyperemesis Syndrome in a Traveler from a Cannabis-Legal Country: A Case Report from Japan
Abstract Cannabinoid hyperemesis syndrome (CHS) is characterized by recurrent nausea, vomiting, and abdominal pain in chronic cannabis users. We report…
Combined Administration of Cannabidiol and L-Theanine Improves Sleep-Related Outcomes in Caffeine-Induced Sleep Disturbances Mouse Model
Abstract Sleep disruption is associated with increased risks of metabolic, cardiovascular, and neuropsychiatric disorders. Cannabidiol (CBD) and L-theanine have attracted…
Medicinal Plants and Their Bioactive Phytochemicals as Emerging Therapeutic Strategies for Alzheimer’s Disease: An Integrative Review of Preclinical and Clinical Evidence
Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by β-amyloid deposition, tau hyperphosphorylation, mitochondrial dysfunction, oxidative stress, neuroinflammation,…