Imaging and Genetic Tools for the Investigation of the Endocannabinoid System in the CNS
Abstract As central nervous system (CNS)-related disorders present an increasing cause of global morbidity, mortality, and high pressure on our…
Science Article
Oxycodone Self-Administration in Female Rats is Enhanced by ∆9-tetrahydrocannabinol, but not by Cannabidiol, in a Progressive Ratio Procedure
Abstract Epidemiological evidence suggests that the legalization of cannabis may reduce opioid-related harms. Preclinical evidence of neuropharmacological interactions of endogenous…
Dermatological evaluation in dogs with atopic dermatitis treated with full-spectrum high cannabidiol oil: a pre study part 1
Abstract Introduction: Dermatological consultations represent a great part of the small animal medical clinic routine. Canine atopic dermatitis (CAD) is…
Cosexuality Reduces Pollen Production and Fitness in Cannabis sativa L.
Abstract Cannabis sativa L. is cultivated globally for its cannabinoid-dense inflorescences. Commercial preference for sinsemilla has led to the development…
Anxiety Modulation by Cannabinoids—The Role of Stress Responses and Coping
Abstract Endocannabinoids were implicated in a variety of pathological conditions including anxiety and are considered promising new targets for anxiolytic…
Pseudocannabinoid H4CBD improves glucose response during advanced metabolic syndrome in OLETF rats independent of increase in insulin signaling proteins
Abstract Cannabidiol (CBD) use has grown exponentially more popular in the last two decades, particularly among older adults (>55 yr),…
Long-term efficacy and adverse effects of cannabidiol in adjuvant treatment of drug-resistant epilepsy: a systematic review and meta-analysis
Abstract Background: Epilepsy is one of the most common chronic brain diseases. Almost one-third of patients have drug-resistant epilepsy (DRE).…
Combining the potential of 3D printed buccal films and nanostructured lipid carriers for personalised cannabidiol delivery
Abstract Graphical Abstract: Supplementary Information: The online version contains supplementary material available at 10.1007/s13346-023-01446-0. Article type: Research Article Keywords: CBD,…
Health, safety, and socioeconomic impacts of cannabis liberalization laws: An evidence and gap map
Abstract Background: Globally, cannabis laws and regulations are rapidly changing. Countries are increasingly permitting access to cannabis under various decriminalization,…
Colloidal aggregation confounds cell-based Covid-19 antiviral screens
Abstract Colloidal aggregation is one of the largest contributors to false-positives in early drug discovery and chemical biology. Much work…