Natural Product-Inspired Dopamine Receptor Ligands
Abstract Due to their evolutionary bias as ligands for biologically relevant drug targets, natural products offer a unique opportunity as…
Science Article
Cannabinoids Block Fat-induced Incretin Release via CB1-dependent and CB1-independent Pathways in Intestinal Epithelium
Abstract Background and Aims: Glucose homeostasis is regulated by a dynamic interplay between hormones along the gastro-insular axis. For example,…
Plant-Based Alternatives to Mold-Ripened Cheeses as an Innovation among Dairy Analogues
Abstract There is a growing demand for vegan products and plant-based food when dealing with the impact of livestock on…
Cannabis therapy in rheumatological diseases: A systematic review
Abstract Cannabis has been used in rheumatic diseases as therapy for chronic pain or inflammatory conditions. Herein, the authors systematically…
Liver Transcriptomic Profiles of Ruminant Species Fed Spent Hemp Biomass Containing Cannabinoids
Abstract The inclusion of spent hemp biomass (SHB), an extracted byproduct from industrial cannabidiol (CBD) production, in the diets of…
QuEChERS Extraction and Simultaneous Quantification in GC-MS/MS of Hexahydrocannabinol Epimers and Their Metabolites in Whole Blood, Urine, and Oral Fluid
Abstract Recently, hexahydrocannabinol (HHC) was posed under strict control in Europe due to the increasing HHC-containing material seizures. The lack…
Prenatal Cannabis Use and Maternal Pregnancy Outcomes
Abstract Question: Is prenatal cannabis use associated with maternal health outcomes during pregnancy? Findings: In this cohort study of 316…
Prenatal broad-spectrum cannabidiol administration prevents an autism-like phenotype in male offspring from a maternal stress/terbutaline rat model
Abstract Recently, the diagnosis of autism spectrum disorder (ASD) has increased from 1 in 150 to every 1 in 36…
The Impacts of Adolescent Cannabinoid Exposure on Striatal Anxiety- and Depressive-Like Pathophysiology Are Prevented by the Antioxidant N-Acetylcysteine
Abstract Background: Exposure to Δ9-tetrahydrocannabinol (THC) is an established risk factor for later-life neuropsychiatric vulnerability, including mood- and anxiety-related symptoms.…
Safety climate in the operating room in the pre-pandemic and pandemic period of COVID-19: A mixed method study
Abstract Introduction: To verify whether the COVID-19 pandemic has had an impact on the safety climate based on the perception…