Chronic Pain and Obsessive–Compulsive Disorder: A Scoping Review
Abstract Introduction: The aim of this study was to map the association between Chronic Pain (CP) and Obsessive–Compulsive Disorder (OCD)…
Science Article
Current Trends in Clinical Trials of Prodrugs
Abstract The development of new drugs is a lengthy and complex process regarding its conception and ideation, passing through in…
Engineering a promiscuous prenyltransferase for selective biosynthesis of an undescribed bioactive cannabinoid analog
Abstract Cannabinoids are unique meroterpenoids, with cannabigerolic acid (CBGA) serving as a dedicated precursor. This study introduces a fungal aromatic…
The Effects of Cannabinoids on Ischemic Stroke-Associated Neuroinflammation: A Systematic Review
Abstract Graphical Abstract: Article type: Review Article Keywords: Stroke, Inflammation, Cannabinoids, Neuroinflammation, Neuroprotection, Astrocytes, Microglia, Blood–Brain Barrier Authors: Eman A.…
Empfehlungen der DGRh-Kommission für Komplementäre Heilverfahren und Ernährung zur Anwendung von ausgewählten Phytotherapeutika und pflanzlichen Präparaten in der Rheumatologie
Abstract Hintergrund: Pflanzliche Präparate und Phytotherapeutika werden für Symptome und Erkrankungen des rheumatischen Formenkreises angeboten und oft intensiv in der…
The Endocannabinoid System: Implications in Gastrointestinal Physiology and Pathology
Abstract The endocannabinoid system (ECS), composed of receptors, endocannabinoids, and enzymes that regulate biosynthesis and degradation, plays a fundamental role…
CB1 Receptor Antagonist Selonabant (ANEB‐001) Blocks Acute THC Effects in Healthy Volunteers: A Phase II Randomized Controlled Trial
Abstract Emergency department visits due to cannabinoid‐induced toxicity, including acute cannabinoid intoxication (ACI) have increased worldwide as more states have…
Comprehensive multi-omics analysis showed that CDC6 is a potential prognostic and immunotherapy biomarker for multiple cancer types including HCC
Abstract We provide a comprehensive picture of the expression landscape of CDC6 in pan-cancer and its close relationship with the…
Neurologists’ perspectives of cannabis-based medicines: results from an all-Ireland survey
Abstract Background: Advancements continue to be made in the development of medicines containing components of the Cannabis sativa L. plant.…
Antimicrobial Potential of Cannabinoids: A Scoping Review of the Past 5 Years
Abstract In the scenario of fighting bacterial resistance to antibiotics, natural products have been extensively investigated for their potential antibacterial…