Beyond Borders: A Longitudinal Study of Nepali Nurses’ Dreams, Realities, and the Pursuit of a Global Career
Abstract The global migration of nurses, particularly from developing nations like Nepal, is a complex tapestry woven with threads of…
Science Article
The role of tetrahydrocannabivarin (THCV) in metabolic disorders: A promising cannabinoid for diabetes and weight management
Abstract Disorders of the metabolism, including obesity and type 2 diabetes, represent significant global health challenges due to their rising…
Cannabis and Polypharmacy Leading to Hospitalization for Acute Confusion and Inability to Ambulate
Abstract Inability to ambulate is a common issue for which an Emergency Department (ED) may request inpatient admission to the…
The major phytocannabinoids, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), affect the function of CatSper calcium channels in human sperm
Abstract STUDY QUESTION: Do the main psychoactive phytocannabinoid delta-9-tetrahydrocannabinol (THC) and its non-psychoactive analog cannabidiol (CBD) affect human sperm function?…
Risk Factors for Narcotic Use in Street Children: A Cross-Sectional Analysis From a Low-Middle-Income Country
Abstract Worldwide, indulgence in high-risk behaviors such as substance abuse is on the rise in street children. Though substance abuse…
Structure modification of luteolin and the influence of its derivatives on biological activities
Abstract Introduction: This research aims to synthesize luteolin derivatives from hemp seeds by means of chemical synthesis, improve the synthesis…
Anti-Infective Screening of Selected Nine Cannabinoids Against Clostridium perfringens and Influenza A (H5N1) Neuraminidases, and SARS-CoV-2 Main Protease and Spike Protein Interactions
Abstract Recently, cannabinoids have gained scientific interest as a promising anti-infective natural product class, as reported in several studies. However,…
Metabolomic profiling of cannabis use and cannabis intoxication in humans
Abstract Acute intoxication from Δ9-tetrahydrocannabinol (THC, the primary active ingredient of cannabis) can lead to neurocognitive impairment and interference with…
Optimizing ethanol-modified supercritical CO₂ extraction for enhanced bioactive compound recovery in hemp seed oil
Abstract This work aimed to extract hemp seed oil using modified supercritical CO2 with ethanol, while optimizing the overall process…
Endocannabinoid system upregulates the enrichment and differentiation of human iPSC- derived spermatogonial stem cells via CB2R agonism
Abstract Background: Male factor infertility (MFI) is responsible for 50% of infertility cases and in 15% of the cases sperm…