In vitro inhibition of voltage-dependent sodium currents by the antifungal drug amorolfine
Abstract Voltage-gated sodium (Nav) channels are critical for electrical signaling, and their pharmacological modulation can be leveraged for the development…
Science Article
State funding for cannabis research: an analysis of funding mechanisms and levels
Abstract Background: This paper examines cannabis research funding across U.S. states that have legalized cannabis for medical or adult (non-medical)…
Region-Specific Impact of Repeated Synthetic Cannabinoid Exposure and Withdrawal on Endocannabinoid Signaling, Gliosis, and Inflammatory Markers in the Prefrontal Cortex and Hippocampus
Abstract Synthetic cannabinoid use raises concerns about its neuroinflammatory effects, including molecular adaptations of the endocannabinoid system (ECS) in the…
Mapping and characterization of a novel powdery mildew resistance locus (PM2) in Cannabis sativa L.
Abstract Introduction: Breeding genetic resistance to economically important crop diseases is the most sustainable strategy for disease management and enhancing…
Cannabidiol-Based Thiosemicarbazones: A Preliminary Study Evaluating Their Anti-Tyrosinase Properties
Abstract Cannabidiol (CBD), a non-psychoactive cannabinoid, has attracted significant research interest due to its antioxidant, anti-inflammatory, and neuroprotective properties. As…
Toxic Exposures in Children: A Review of Emergency Department Transfers to a Tertiary Pediatric Hospital
Abstract Objectives: Pediatric poisonings are a common emergency department (ED) presentation. In some instances, the first hospital may not have…
Species distribution of Cannabis sativa: Past, present and future
Abstract Cannabis sativa L. is an annual flowering herb of Eurasian origin that has long been associated with humans. Domesticated…
UK Medical Cannabis Registry: An Analysis of Outcomes of Medical Cannabis Therapy for Hypermobility‐Associated Chronic Pain
Abstract Objective: The study aims to evaluate the clinical outcomes in patients with hypermobility spectrum disorder (HSD) and hypermobile Ehlers–Danlos…
Compassion through technology: Digital empathy concept analysis and implications in nursing
Abstract Objective: Digital empathy is an emerging concept in telehealth nursing, emphasizing emotional engagement and compassionate communication in virtual care…
Beyond Borders: A Longitudinal Study of Nepali Nurses’ Dreams, Realities, and the Pursuit of a Global Career
Abstract The global migration of nurses, particularly from developing nations like Nepal, is a complex tapestry woven with threads of…