Landscape of BRAF transcript variants in human cancer
Abstract The BRAFV600E mutant kinase is widely studied as a cancer driver and therapeutic target. Here, we investigated how the…
Science Article
The Potential Use of Cannabidiol in the Treatment of Opioid Use Disorder: A Systematic Review
Abstract Trial Registration: PROSPERO identifier: CRD42023401446 Article type: Review Article Keywords: addiction, cannabidiol, opioid, opioid use disorder, tetrahydrocannabinol, withdrawal Authors:…
Discovery of major QTL and a massive haplotype associated with cannabinoid biosynthesis in drug‐type Cannabis
Abstract Cannabis (Cannabis sativa L.), once sidelined by decades of prohibition, has now gained recognition as a multifaceted and promising…
The role of RETN in stomach adenocarcinoma (STAD): insights from pan-cancer analysis of RNA-seq data based on the TCGA database
Abstract Objective: To analyze the expression and significance of resistin (RETN) in pan-cancer and determine the prospect of RETN as…
Recent HPLC-UV Approaches for Cannabinoid Analysis: From Extraction to Method Validation and Quantification Compliance
Abstract Since the 1990s, cannabis has experienced a gradual easing of access restrictions, accompanied by the expansion of its legalization…
Rapid Specific PCR Detection Based on THCAS and CBDAS for the Prediction of Cannabis sativa Chemotypes: Drug, Fiber, and Intermediate
Abstract Cannabis sativa L. is divided into three main groups: drug-type, intermediate-type, and fiber-type. The presence of tetrahydrocannabinol (THC) exceeding…
Sociodemographic and clinical characteristics associated with overdose among patients with a substance-related diagnosis in the emergency department of Southern California
Abstract Background: Drug overdoses are a significant public health concern, but there is limited research on the associated factors among…
Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review
Abstract The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal…
Opioid Use Following Primary Unilateral Total Knee Arthroplasty Varies With Age
Abstract Background: Reducing unused prescribed opioids following arthroplasty procedures remains a challenge. The relationship between opioid consumption and age has…
Cannabidiol as an immune modulator: A comprehensive review
Abstract Cannabidiol (CBD), a non-psychoactive phytocannabinoid derived from Cannabis sativa, has emerged as a promising therapeutic agent due to its…