The critical role of ion channels in kidney disease: perspective from AKI and CKD
Abstract Ion channels, particularly those in the transient receptor potential (TRP) family, play key roles in cellular stress responses like…
Science Article
Re-do laparoscopic common bile duct exploration for recurrent common bile duct stones: a single-center retrospective cohort study
Abstract Purpose: Common bile duct (CBD) stone recurrence after laparoscopic CBD exploration (LCBDE) is relatively common. No studies have been…
A preliminary randomized trial of the safety, tolerability, and clinical effects of hemp-derived cannabidiol in alcohol use disorder
Abstract Introduction: Cannabidiol (CBD) has recently gained attention for its potential therapeutic effects in substance use disorders, including Alcohol Use…
Beyond Cannabidiol: The Contribution of Cannabis sativa Phytocomplex to Skin Anti-Inflammatory Activity in Human Skin Keratinocytes
Abstract Background: Cannabis sativa L. (C. sativa) has a long history of medicinal use. Its inflorescences contain bioactive compounds like…
Cannabidiol and nano-selenium mediate intestinal barrier function by affecting mucosal microstructures, and gut-associated immunological and oxidative stress response in the gut of chickens infected with C. perfringens
Abstract Nutritional additives with biological activity, such as cannabidiol (CBD) and nano-selenium (nano-Se), are viable to prevent bacterial diseases such…
Staphylococcus aureus AgrA Modulators From South African Antimicrobial Plants
Abstract South African plants are an underutilized metabolite source for novel antimicrobials targeting key quorum sensing (QS) systems like the…
Biodegradation of Juglone by Xanthomonas arboricola pv. juglandis, the Causal Agent of Walnut (Juglans regia L.) Bacterial Blight
Abstract Xanthomonas arboricola pv. juglandis is the causal agent of walnut blight, a disease affecting Juglans regia L. cultivations by…
SLC16A3 (MCT4) expression in tumor immunity and Metabolism: Insights from pan-cancer analysis
Abstract Background: SLC16A3, a highly expressed H + -coupled symporter, facilitates lactate transport via monocarboxylate transporters (MCTs), contributing to acidosis.…
Fatty Acid Composition and Bioactive Profiles in the Aerial Parts of Cannabis sativa
Abstract The interest in Cannabis sativa L. has been on the rise recently, driven by its potential applications in various…
Therapeutic Effect of Lebanese Cannabis Oil Extract in the Management of Sodium Orthovanadate-Induced Nephrotoxicity in Rats
Abstract Sodium orthovanadate is a non-selective protein tyrosine phosphatase inhibitor that can cause several types of kidney injury, including glomerulosclerosis,…