Pharmacological mechanism of natural antidepressants: the role of epigenetic modifications
Abstract MDD is a complex mental illness shaped by the interplay between genetic vulnerability and environmental triggers. Its underlying pathophysiological…
Science Article
A systematic review investigating prenatal cannabis and tobacco co-exposure: Impacts on neonatal, behavioral, cognitive and physiological outcomes
Abstract Background: Despite the high and increasing rates of cannabis and nicotine/tobacco product (NTP) use during pregnancy, the impact of…
Evaluation of peri-implant health and whole salivary cortisol levels in adults with mental health disorders
Abstract The null hypothesis was that there is no difference in whole salivary cortisol levels (CL) and peri-implant health status…
Water use and productivity of Cannabis sativa L., KwaZulu-Natal Midlands, South Africa
Abstract Aims: The South African National Water Act (No. 36 of 1998) mandates the regulation of land-based activities that reduce…
Cannabidiol (CBD) and cognitive function in older adults: a mini review
Abstract As the global population ages, the need for effective interventions to support cognitive health in older adults is growing.…
Metabolism of Cannabidiol in Respiratory-Associated Cells and HepG2-Derived Cells and Molecular Docking of Cannabidiol and Its Metabolites with CYP Enzymes and Cannabinoid Receptors
Abstract Cannabidiol (CBD) has been reported in medical applications for various indications. The enzymatic metabolism of CBD is not fully…
Orally Administered CBD/CBG Hemp Extract Reduces Severity of Ulcerative Colitis and Pain in a Murine Model
Abstract Background: Ulcerative colitis (UC) is an autoimmune disorder characterized by inflammation of the mucosa that gives rise to a…
The predictivity of hematological parameters and related inflammatory biomarkers of male subjects with chronic polysubstance use disorder
Abstract Background: Polysubstance use disorder (PSUD) is a chronic disease with adverse clinical outcomes. Hematological properties and related inflammatory biomarkers…
Study protocol of a pilot randomized controlled trial of transcranial direct current stimulation paired with reappraisal training for treatment of cannabis use disorder
Abstract Introduction: As legalization of cannabis products continues, cannabis use becomes more prevalent, and concerns regarding cannabis use disorder (CUD)…
Pan-Genome Analysis of Cannabis sativa: Insights on Genomic Diversity, Evolution, and Environment Adaption
Abstract Cannabis sativa is a crop which has been cultivated since ancient times, with important cultural and industrial value. Due…