Modulatory Effects of “Minor” Cannabinoids in an in vitro Model of Neuronal Hypersensitivity
Abstract Aim: Effective treatment for neuropathic pain remains an unmet clinical need. The therapeutic benefits of the Cannabis plant are…
Science Article
Cannabis-based extract for managing pain in dogs with osteoarthritis: efficacy and safety assessment
Abstract Introduction: Canine osteoarthritis (OA) is a prevalent disease characterized by progressive joint degeneration, pain, and impaired mobility. In older…
Durable complete response of advanced hepatocellular carcinoma using cannabis oil: a report of two cases
Abstract Background: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide with a grim prognosis. Current treatment options…
A novel protocol for protoplast isolation, transfection, and culture in Cannabis sativa L
Abstract Background: Protoplasts are a valuable tool for studying gene expression and applying genome editing techniques. Given the high medicinal…
Comparative effects of Berberis vulgaris extract and casein nanocapsules on the antioxidant activity and oxidative stability of selected vegetable oils
Abstract This study aimed to enhance the stability and functionality of Berberis vulgaris anthocyanins through casein-based encapsulation and to evaluate…
Cannabis Use and Glutamate across the Psychosis Spectrum: In Vivo Evidence from 7T Proton Magnetic Resonance Spectroscopy
Abstract Cannabis use is linked to elevated psychosis risk, yet the neurobiological mechanisms that couple use to symptom expression remain…
The cannabis-mind connection: a clinician’s perspective on mental health practice, harm reduction, and racial equity
Abstract Background: Cannabis is increasingly part of the mental health landscape, yet clinical practice has not kept pace with patient…
Genotype and chemotype insights of high-THC medicinal Cannabis sativa L.: the role of SSR markers in the identification of cultivars
Abstract Background: Standardized methods for distinguishing high-THC Cannabis sativa L. genotype versus chemotype of cultivars remain limited, posing challenges for…
Insights into cannabinoid receptor 2 (CB2) anterograde trafficking and pharmacological chaperoning
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00018-025-05961-w. Article type: Research Article Keywords: Receptor, cannabinoid, Cannabinoid…
Semi-Quantitative On-Site Microfluidic Assay to Detect 11-Nor-9-carboxy-delta 9-Tetrahydrocannabinol (THC-COOH) in Urine
Abstract Highlights: What are the main findings? What are the implications of the main findings? Abstract: The rapid detection of…