RERE-AS1 as a regulator of immune modulation and therapeutic response in breast cancer
Abstract Background and aims: Breast cancer (BRCA) remains one of the most prevalent malignancies and a major threat to women’s…
Science Article
Effects and safety of a CBD-rich Cannabis sativa oil in knee osteoarthritis: a double-blind, randomized, placebo-controlled trial – CANOA – cannabis for osteoarthritis
Abstract Methods: Osteoarthritis patients were randomized into either placebo or cannabis groups and monitored for 60 days. The cannabis group…
The impact of mobile health interventions on maternal-neonatal outcomes in women with gestational diabetes mellitus: a systematic review and meta-analysis
Abstract Background: Gestational diabetes mellitus (GDM), a prevalent complication during pregnancy, is closely associated with an elevated risk of adverse…
Advances in Targeting Growth Factor Signalling in Neuroblastoma and Overcoming Drug Resistance
Abstract Neuroblastoma is an embryonal tumour that arises from the malignant transformation of neural crest cells and remains one of…
Cross-sectional comparison of cannabis use in adults with neuropathic versus non-neuropathic pain
Abstract Introduction: Cannabis has been decriminalized by many states and shows promise in treating both neuropathic and non-neuropathic pain through…
Peroxisomes, PPARs, and Their Role in Macrophages
Abstract Macrophages are versatile immune cells capable of modifying their functions based on their location and the specific requirements of…
Biofilm structure as a key factor in antibiotic tolerance: insights from Bacillus subtilis model systems
Abstract Tolerance to antimicrobial agents in mature and structured biofilms presents a significant challenge in clinical and industrial applications. The…
METTL3-mediated m6A modification of TACSTD2 mRNA inhibits papillary thyroid cancer progression by activating the TNF signaling and blocking epithelial–mesenchymal transition
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-30448-w. Article type: Research Article Keywords: Papillary thyroid cancer,…
Characterizing proximal risk for depressive symptoms and suicidal ideation with acute cannabis use and withdrawal among adolescents using ecological momentary assessment: Study protocol
Abstract Background: Heavy cannabis use often co-occurs with symptoms of depression in adolescents. Adolescents with past-year cannabis use are at…
Transgastric ERCP is a Useful Modality for Addressing Biliary Complications in Patients After Orthotopic Liver Transplantation and History of Roux‐en‐Y Gastric Bypass: Case Report and Proposed Treatment Algorithm
Abstract Biliary complications after orthotopic liver transplantation (OLTx) have a high incidence with inherent risks. Given the rise of obesity…